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Murray State vs. Drake prediction: Murray State favored to win men's college basketball matchup [1/21/2026]
Get Murray State vs Drake predictions for college basketball Wednesday.

Men's college basketball action continues on Wednesday at 7:00 PM ET as Murray State takes on Drake in men's college basketball action at Knapp Center.
Based on updated simulation results, Dimers' proven college basketball model predicts Murray State as the most likely winner of the Murray State vs. Drake game.
This article offers further insights into Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.
Murray State vs. Drake prediction: Who will win and cover?
Using innovative machine learning and data, we have simulated the result of Wednesday's NCAA basketball matchup between Murray State and Drake 10,000 times as part of our men's college basketball predictions coverage.
Our leading predictive model gives Murray State a 64% chance of beating Drake. Our predicted final score has Murray State winning 79-75.
According to our model, Drake (+4.5) has a 51% chance of covering the spread, while the over/under total of 156.5 points has a 55% chance of staying under.
Murray State vs. Drake odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Murray State | Drake |
|---|---|---|
| Spread | -4.5 (-110) | +4.5 (-110) |
| Moneyline | -200 | +176 |
| Total | o156.5 (-110) | u156.5 (-105) |
All odds are correct at the time of publication and are subject to change.
Murray State vs. Drake picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Drake +4.5 | -110 |
| Moneyline | Drake | +176 |
| Total | Under 156.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is Under 156.5 total points.
Murray State vs. Drake game-day updates and essential details
Wednesday's men's college basketball game between Drake and Murray State at Knapp Center is scheduled to commence at 7:00 PM ET.
- Who: Murray State vs. Drake
- Date: Wednesday, January 21, 2026
- Time: 7:00 PM ET/4:00PM PT
- Venue: Knapp Center
Conclusion
We predict Murray State, with a 64% win probability, will likely beat Drake on Wednesday.
AI and automation have enhanced this article to quickly deliver accurate Murray State vs. Drake insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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