Home run predictions for Blue Jays vs. Mariners Game 3 include Cal Raleigh, Julio Rodriguez [10/15/2025]

Our MLB home run predictions for Wednesday, October 15, 2025, are in—with Cal Raleigh leading the list based on the latest Dimers Pro simulation data.

Wednesday's HR projections pull from our full list of home run predictions, which simulate every MLB playoffs matchup 10,000 times to reveal the top home run picks today.

Home run predictions for October 15, 2025

Our analysis shows Raleigh leads today's MLB home run predictions with a 22.6% chance to go yard, followed by Eugenio Suarez (18.6%) and Anthony Santander (17.2%).

Daulton Varsho and Julio Rodriguez are among several other sluggers to rank inside the top 10. Want the full list of home run props today—including every player's HR prediction for Wednesday? Join Dimers Pro now.

Already a Dimers Pro member? Check out today's HR and hitter projections and sort by “To Hit HR” to see every player’s probability of going deep.

Wednesday's playoffs home run picks [10/15/2025]

After running 10,000 simulations per matchup and assessing key variables like weather and pitching matchups, Dimers Pro has identified one of the best MLB home run props today.

Anthony Santander (Blue Jays) to hit a home run

• Probability: 16.7%
• Odds: +675
• Edge: 3.8%
• Game: Blue Jays vs. Mariners (8:08PM ET)
• Pitching matchup: George Kirby

Ranked as one of the top three most likely players in today's home run predictions, Toronto slugger Anthony Santander offers standout value at +675 with BetMGM, showing an edge of 3.8%—making him one of the strongest home run bets today.

With George Kirby on the mound for the Mariners, factoring in both projection edge and odds, Santander has emerged as the one of the best home run picks today on Wednesday's slate.

For more expert MLB picks and data-backed MLB predictions, join Dimers Pro now. Pro users get full access to a total of 18 home run predictions today, plus hit and RBI projections, pitcher props, and more—perfect for building smarter MLB parlays and round robins.

MLB postseason schedule for today [Wednesday, October 15, 2025]

• Blue Jays vs. Mariners (8:08PM ET, Wednesday)

Conclusion

For October 15, 2025, our MLB home run predictions are locked in, with sluggers like Cal Raleigh, Eugenio Suarez and Anthony Santander projected to be among the most powerful bats in today’s games. Santander in particular stands out as the best value bet, offering an appealing 3.8% edge at +675 odds.

These insights are based on 10,000 game simulations and are designed to help you identify smarter betting opportunities. As always, gamble responsibly. If you or someone you know needs support, call 1-800-GAMBLER.

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