Home run predictions for Blue Jays vs. Mariners include Cal Raleigh, Daulton Varsho [10/17/2025]

Our MLB home run predictions for Friday, October 17, 2025, are here—with Cal Raleigh topping the list according to the latest Dimers Pro simulation data.

Friday's HR projections come straight from our home run predictions, which simulate every MLB playoffs matchup 10,000 times to reveal the top slugging candidates today.

Home run predictions for October 17, 2025

Our analysis shows Raleigh leads today's MLB home run predictions with a 21.9% chance to go yard, followed by Eugenio Suarez (19.8%) and Julio Rodriguez (16.9%).

Vladimir Guerrero and Daulton Varsho are among several other sluggers to crack the top 10. Want the full list of home run props today—including every player's HR prediction for Friday? Join Dimers Pro now.

Already a Dimers Pro member? Check out today's HR and hitter projections and sort by “To Hit HR” to see every player’s probability of going deep.

Friday's playoffs home run picks [10/17/2025]

After running 10,000 simulations per matchup and evaluating key factors like weather and pitching matchups, Dimers Pro has identified one of the best MLB home run props today.

Dominic Canzone (Mariners) to hit a home run

• Probability: 15.2%
• Odds: +770
• Edge: 3.7%
• Game: Blue Jays vs. Mariners (6:08PM ET)
• Pitching matchup: Kevin Gausman

Ranked as one of the top 10 in today's home run predictions, Seattle slugger Dominic Canzone offers standout value at +770 with DraftKings Sportsbook, showing an edge of 3.7%—making him one of the strongest home run bets today.

In a matchup against Blue Jays starter Kevin Gausman, Canzone shapes up as one of the best home run picks today on Friday's slate.

For more expert MLB picks and data-led MLB predictions, join Dimers Pro now. Pro users get full access to a total of 11 home run predictions today, plus hit and RBI projections, pitcher props, and more—perfect for building smarter MLB parlays and round robins.

MLB postseason schedule for today [Friday, October 17, 2025]

• Blue Jays vs. Mariners (6:08PM ET, Friday)

Conclusion

For October 17, 2025, our MLB home run predictions are locked in, with sluggers like Cal Raleigh, Eugenio Suarez and Julio Rodriguez projected to be among the most powerful bats in today’s games. But it's Dominic Canzone who stands out as the best value bet, offering an appealing 3.7% edge at +770 odds.

These insights are based on 10,000 game simulations and are designed to help you identify smarter betting opportunities. As always, gamble responsibly. If you or someone you know needs support, call 1-800-GAMBLER.

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