Missouri vs. Kentucky prediction: Kentucky favored to win men's college basketball matchup [1/7/2026]

Kentucky and Missouri will meet in men's college basketball action at Rupp Arena on Wednesday, starting at 7:00 PM ET.

Based on the latest simulation results, Dimers' advanced college basketball model predicts Kentucky as the most likely winner of the Missouri vs. Kentucky game.

This article offers a closer look at Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Missouri vs. Kentucky prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the result of Wednesday's NCAA basketball game between Missouri and Kentucky 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Kentucky a 91% chance of defeating Missouri. Our predicted final score has Kentucky winning 84-69.

According to our model, Kentucky (-12.5) has a 57% chance of covering the spread, while the 150.5-point over/under has a 53% chance of going over.

Missouri vs. Kentucky odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Missouri vs. Kentucky picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: