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Mississippi State vs. LSU prediction: LSU favored to win men's college basketball matchup [1/28/2026]

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Written by Mac Douglass

Get Mississippi State vs LSU predictions for college basketball Wednesday.

Mississippi State-LSU Predictions and Game Preview.
Mississippi State vs. LSU men's college basketball prediction for Wednesday, January 28, 2026.

LSU and Mississippi State are scheduled to meet in men's college basketball action at Pete Maravich Assembly Center on Wednesday, starting at 7:00 PM ET.

Based on the latest simulation results, Dimers' proven college basketball model predicts LSU as the most likely winner of the Mississippi State vs. LSU game.

This article offers an expanded analysis of Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Mississippi State vs. LSU prediction: Who will win and cover?

Using innovative machine learning and data analysis, we have simulated the outcome of Wednesday's NCAA basketball game between Mississippi State and LSU 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives LSU a 77% chance of defeating Mississippi State. Our predicted final score has LSU winning 81-73.

According to our model, LSU (-7.5) has a 51% chance of covering the spread, while the over/under total of 154.5 points has a 52% chance of going over.

 

Mississippi State vs. LSU odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

Bet Type Mississippi State LSU
Spread +7.5 (-110) -7.5 (-105)
Moneyline +275 -325
Total o154.5 (-108) u154.5 (-110)

All odds are correct at the time of publication and are subject to change.

Mississippi State vs. LSU picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread LSU -7.5 -105
Moneyline LSU -325
Total Over 154.5 -108

According to our men's college basketball best bets, the top play to make on this game is LSU to win.

 

Mississippi State vs. LSU game-day updates and essential details

Wednesday's men's college basketball action between LSU and Mississippi State at Pete Maravich Assembly Center is scheduled to commence at 7:00 PM ET.

  • Who: Mississippi State vs. LSU
  • Date: Wednesday, January 28, 2026
  • Time: 7:00 PM ET/4:00PM PT
  • Venue: Pete Maravich Assembly Center

Conclusion

We predict LSU, with a 77% win probability, will likely beat Mississippi State on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Mississippi State vs. LSU insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Mac Douglass
Senior Editor

Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.

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