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Mississippi State vs. LSU prediction: LSU favored to win men's college basketball matchup [1/28/2026]
Get Mississippi State vs LSU predictions for college basketball Wednesday.

LSU and Mississippi State are scheduled to meet in men's college basketball action at Pete Maravich Assembly Center on Wednesday, starting at 7:00 PM ET.
Based on the latest simulation results, Dimers' proven college basketball model predicts LSU as the most likely winner of the Mississippi State vs. LSU game.
This article offers an expanded analysis of Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.
Mississippi State vs. LSU prediction: Who will win and cover?
Using innovative machine learning and data analysis, we have simulated the outcome of Wednesday's NCAA basketball game between Mississippi State and LSU 10,000 times as part of our men's college basketball predictions coverage.
Our famous predictive model currently gives LSU a 77% chance of defeating Mississippi State. Our predicted final score has LSU winning 81-73.
According to our model, LSU (-7.5) has a 51% chance of covering the spread, while the over/under total of 154.5 points has a 52% chance of going over.
Mississippi State vs. LSU odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Mississippi State | LSU |
|---|---|---|
| Spread | +7.5 (-110) | -7.5 (-105) |
| Moneyline | +275 | -325 |
| Total | o154.5 (-108) | u154.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Mississippi State vs. LSU picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | LSU -7.5 | -105 |
| Moneyline | LSU | -325 |
| Total | Over 154.5 | -108 |
According to our men's college basketball best bets, the top play to make on this game is LSU to win.
Mississippi State vs. LSU game-day updates and essential details
Wednesday's men's college basketball action between LSU and Mississippi State at Pete Maravich Assembly Center is scheduled to commence at 7:00 PM ET.
- Who: Mississippi State vs. LSU
- Date: Wednesday, January 28, 2026
- Time: 7:00 PM ET/4:00PM PT
- Venue: Pete Maravich Assembly Center
Conclusion
We predict LSU, with a 77% win probability, will likely beat Mississippi State on Wednesday.
AI and automation have enhanced this article to quickly deliver accurate Mississippi State vs. LSU insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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