Mississippi State vs. Kentucky prediction: Kentucky favored to win men's college basketball matchup [1/10/2026]

Kentucky will square off with Mississippi State in men's college basketball action at Rupp Arena on Saturday, beginning at 8:30 PM ET.

Based on updated simulation results, Dimers' proven college basketball model predicts Kentucky as the most likely winner of the Mississippi State vs. Kentucky game.

This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Mississippi State vs. Kentucky prediction: Who will win and cover?

Using innovative machine learning and data analysis, we have simulated the outcome of Saturday's NCAA basketball matchup between Mississippi State and Kentucky 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model currently gives Kentucky an 88% chance of beating Mississippi State. Our predicted final score has Kentucky winning 84-70.

According to our model, Kentucky (-10.5) has a 58% chance of covering the spread, while the 152.5-point over/under has an equal 50-50 chance of hitting.

Mississippi State vs. Kentucky odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Mississippi State vs. Kentucky picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: