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Minnesota vs. Missouri prediction: Why Missouri is favored to win men's college basketball matchup [11/12/2025]
Get Minnesota vs Missouri predictions for college basketball Wednesday.

Missouri and Minnesota will meet in men's college basketball action at Mizzou Arena on Wednesday, starting at 8:00PM ET.
Based on updated simulation results, Dimers' proven college basketball model predicts Missouri as the most likely winner of the Minnesota vs. Missouri game.
This article offers further insights into Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.
Minnesota vs. Missouri prediction: Who will win, cover the spread?
Using powerful machine learning and data, we have simulated the outcome of Wednesday's NCAA basketball matchup between Minnesota and Missouri 10,000 times as part of our men's college basketball predictions coverage.
Our leading predictive model currently gives Missouri a 75% chance of beating Minnesota. Our predicted final score has Missouri winning 81-74.
According to our model, Missouri (-6.5) has a 53% chance of covering the spread, while the 158.5-point over/under has a 52% chance of staying under.
Minnesota vs. Missouri odds
We have researched the best Men's College Basketball odds in America for this game, which are listed here:
| Bet Type | Minnesota | Missouri |
|---|---|---|
| Spread | +6.5 (-104) | -6.5 (-118) |
| Moneyline | +260 | -320 |
| Total | o158.5 (-105) | u158.5 (-105) |
All odds are correct at the time of publication and are subject to change.
Minnesota vs. Missouri picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Missouri -6.5 | -118 |
| Moneyline | Missouri | -320 |
| Total | Under 158.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is Under 158.5 total points.
Minnesota vs. Missouri game-day updates and essential details
Wednesday's men's college basketball action between Missouri and Minnesota at Mizzou Arena is scheduled to begin at 8:00PM ET.
- Who: Minnesota vs. Missouri
- Date: Wednesday, November 12, 2025
- Time: 8:00PM ET/5:00PM PT
- Venue: Mizzou Arena
Conclusion
We predict Missouri, with a 75% win probability, will likely beat Minnesota on Wednesday.
AI and automation have enhanced this article to quickly deliver accurate Minnesota vs. Missouri insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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