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Timberwolves vs. Knicks prediction: New York to win, Jalen Brunson projected for big game in Wednesday's NBA matchup [11/5/2025]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Minnesota Timberwolves vs New York Knicks predictions for NBA Wednesday.
The New York Knicks will take on the Minnesota Timberwolves in NBA action at Madison Square Garden on Wednesday, commencing at 7:30PM ET.
Based on the latest simulations and today’s injury reports, Dimers' advanced NBA model predicts the Knicks as the most likely winner of the Timberwolves vs. Knicks game.
This prediction follows the latest NBA Injury Report, which suggests the Knicks lineup will feature players like Jalen Brunson, Karl-Anthony Towns and OG Anunoby, while the Timberwolves will be led by Anthony Edwards, Julius Randle and Jaden McDaniels.
This article offers further insights into Wednesday's matchup, including an expanded look at the predicted score, best bets and player prop picks.
Wolves vs. Knicks prediction: Who will win, cover the spread?
Using innovative machine learning and data, we have simulated the outcome of Wednesday's NBA game between the Timberwolves and Knicks 10,000 times as part of our NBA predictions coverage.
Our leading predictive model currently gives the Knicks a 60% chance of defeating the Timberwolves. Our predicted final score has the Knicks winning 115-113.
According to our model, the Timberwolves (+3.5) have a 52% chance of covering the spread, while the over/under total of 228.5 points has a 51% chance of going over.
Timberwolves vs. Knicks odds
We have sourced the best NBA odds in America for this game, which are listed here:
| Bet Type | Timberwolves | Knicks |
|---|---|---|
| Spread | +3.5 (-105) | -3.5 (-110) |
| Moneyline | +140 | -160 |
| Total | o228.5 (-106) | u228.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Timberwolves vs. Knicks picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Timberwolves +3.5 | -105 |
| Moneyline | Timberwolves | +140 |
| Total | Over 228.5 | -106 |
According to our best NBA bets for Wednesday, the top play to make on this game is Timberwolves +3.5 at the spread.
Timberwolves vs. Knicks player props
Looking for Minnesota vs. New York NBA prop bets? We have crunched the numbers to project how each team's leading players will perform at Madison Square Garden.
Anthony Edwards is expected to lead the Timberwolves with 25 points, 6 rebounds and 5 assists, while Jalen Brunson is projected to have 28 points, 3 rebounds and 6 assists for the Knicks.
Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and more, for every game this season.
Timberwolves prediction
Our model's projected player stats for the Timberwolves are:
| Player | PTS | REB | AST | 3PM |
|---|---|---|---|---|
| Anthony Edwards | 25 | 6 | 5 | 3 |
| Julius Randle | 22 | 6 | 5 | 2 |
| Jaden McDaniels | 14 | 5 | 2 | 1 |
| Donte DiVincenzo | 13 | 4 | 4 | 3 |
| Naz Reid | 10 | 5 | 2 | 2 |
Knicks prediction
Projected points, rebounds, assists and three-pointers made for the Knicks:
| Player | PTS | REB | AST | 3PM |
|---|---|---|---|---|
| Jalen Brunson | 28 | 3 | 6 | 2 |
| Karl-Anthony Towns | 20 | 10 | 2 | 2 |
| OG Anunoby | 17 | 5 | 2 | 3 |
| Mikal Bridges | 16 | 4 | 4 | 2 |
| Jordan Clarkson | 9 | 2 | 2 | 1 |
Wolves vs. Knicks game-day updates and essential details
Wednesday's action between the Knicks and Timberwolves at Madison Square Garden is scheduled to commence at 7:30PM ET.
- Who: Minnesota Timberwolves vs. New York Knicks
- Date: Wednesday, November 5, 2025
- Time: 7:30PM ET/4:30PM PT
- Venue: Madison Square Garden
Conclusion
We predict the Knicks, with a 60% win probability, will likely beat the Timberwolves on Wednesday.
AI and automation have enhanced this article to quickly deliver accurate Timberwolves vs. Knicks insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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