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Bucks vs. Pistons prediction: Detroit favored to win Saturday's NBA matchup [12/6/2025]

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Written by Ryan Leaver

Get Milwaukee Bucks vs Detroit Pistons predictions for NBA Saturday.

Milwaukee Bucks-Detroit Pistons Predictions and Game Preview.
Milwaukee Bucks vs. Detroit Pistons NBA prediction for Saturday, December 6, 2025.

NBA action continues on Saturday at 7:30PM ET as the Milwaukee Bucks face off with the favored Detroit Pistons at Little Caesars Arena.

Based on updated simulations and today’s injury updates, Dimers' proven NBA model predicts the Pistons as the most likely winner of the Bucks vs. Pistons game.

This prediction follows the latest NBA Injury Report, which suggests the Pistons lineup will feature players like Cade Cunningham, Jalen Duren and Tobias Harris, while the Bucks will be led by Kevin Porter, Ryan Rollins and Kyle Kuzma.

This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Bucks vs. Pistons prediction: Who will win and cover?

Using trusted machine learning and data analysis, we have simulated the result of Saturday's NBA matchup between the Bucks and Pistons 10,000 times as part of our NBA predictions coverage.

Our famous predictive model gives the Pistons an 81% chance of defeating the Bucks. Our predicted final score has the Pistons winning 117-107.

According to our model, the Bucks (+12.5) have a 56% chance of covering the spread, while the over/under total of 224.5 points has an equal 50-50 chance of hitting.

 

Bucks vs. Pistons odds

We have researched the best NBA odds in America for this game, which are listed here:

Bet Type Bucks Pistons
Spread +12.5 (-110) -12.5 (-108)
Moneyline +500 -650
Total o224.5 (-110) u224.5 (-110)

All odds are correct at the time of publication and are subject to change.

Bucks vs. Pistons picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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