Michigan State vs. Oregon prediction: Michigan State favored to win men's college basketball matchup [1/20/2026]

Oregon will take on the favored Michigan State in men's college basketball action at Matthew Knight Arena on Tuesday, beginning at 9:00 PM ET.

Based on the latest simulations, Dimers' proven college basketball model predicts Michigan State as the most likely winner of the Michigan State vs. Oregon game.

This article offers a closer look at Tuesday's matchup, including an expanded look at the predicted score, best bets and picks.

Michigan State vs. Oregon prediction: Who will win and cover?

Using powerful machine learning and statistical analysis, we have simulated the outcome of Tuesday's NCAA basketball matchup between Michigan State and Oregon 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model gives Michigan State an 84% chance of defeating Oregon. Our predicted final score has Michigan State winning 75-65.

According to our model, Oregon (+11.5) has a 56% chance of covering the spread, while the over/under total of 137.5 points has a 54% chance of going over.

Michigan State vs. Oregon odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Michigan State vs. Oregon picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: