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Mercer vs. Eastern Kentucky prediction: Why Eastern Kentucky is favored to win men's college basketball matchup [11/22/2025]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Mercer vs Eastern Kentucky predictions for college basketball Saturday.
Men's college basketball action continues on Saturday at 3:00PM ET as Mercer squares off with Eastern Kentucky in men's college basketball action at Baptist Health Arena.
Based on updated simulation results, Dimers' proven college basketball model projects Eastern Kentucky as the most likely winner of the Mercer vs. Eastern Kentucky game.
This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.
Mercer vs. Eastern Kentucky prediction: Who will win and cover?
Using innovative machine learning and data, we have simulated the result of Saturday's NCAA basketball matchup between Mercer and Eastern Kentucky 10,000 times as part of our men's college basketball predictions coverage.
Our independent predictive model currently gives Eastern Kentucky a 65% chance of defeating Mercer. Our predicted final score has Eastern Kentucky winning 82-77.
According to our model, Eastern Kentucky (-4.5) has a 51% chance of covering the spread, while the over/under total of 164.5 points has a 53% chance of staying under.
Mercer vs. Eastern Kentucky odds
We have researched the best Men's College Basketball odds in America for this game, which are listed here:
| Bet Type | Mercer | Eastern Kentucky |
|---|---|---|
| Spread | +4.5 (-110) | -4.5 (-108) |
| Moneyline | +164 | -180 |
| Total | o164.5 (-110) | u164.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Mercer vs. Eastern Kentucky picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Eastern Kentucky -4.5 | -108 |
| Moneyline | Eastern Kentucky | -180 |
| Total | Under 164.5 | -110 |
According to our men's college basketball best bets, the top play to make on this game is Eastern Kentucky to win.
Mercer vs. Eastern Kentucky game-day updates and essential details
Saturday's men's college basketball action between Eastern Kentucky and Mercer at Baptist Health Arena is scheduled to commence at 3:00PM ET.
- Who: Mercer vs. Eastern Kentucky
- Date: Saturday, November 22, 2025
- Time: 3:00PM ET/12:00PM PT
- Venue: Baptist Health Arena
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Conclusion
We predict Eastern Kentucky, with a 65% win probability, will likely beat Mercer on Saturday.
AI and automation have enhanced this article to quickly deliver accurate Mercer vs. Eastern Kentucky insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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