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Men's college basketball picks today: Wednesday's best bets include Southern Illinois vs. Nevada play [11/12/2025]

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Written by Jason Bevilacqua

Get college basketball picks and best bets for Wednesday, November 12, 2025.

Men's College Basketball Best Bets.
These men's college basketball betting picks for November 12, 2025, are based on the latest odds and probabilities for Wednesday's games.

Today’s men's college basketball picks for November 12, 2025 are here, with Southern Illinois vs. Nevada among the top plays identified by our model across Wednesday’s men's college basketball action.

Dimers’ predictive analytics engine runs 24/7, going over the latest men's college basketball odds to uncover legitimate betting edges. The result? Data-backed picks that help Dimers Pro members make smarter decisions.

List of NCAAM picks tonight [11/12, updated 9:38PM ET]

Below, you’ll find today’s top 10 men's college basketball bets, ranked by edge for Wednesday, November 12, 2025.

Nevada -10.5 (-110)

Our model has identified value on Nevada -10.5 at -110 odds. A 55% probability produces an edge of 2.6%, making this the strongest play for today's men's college basketball slate.

 

Southern Illinois vs. Nevada under 151.5 points (-105)

Southern Illinois vs. Nevada under 151.5 points carries a 2.6% edge and a probability of 53.8% at -105 odds, according to our model.

 

Purdue +3.5 (-105)

A 4.6% edge and 55.8% probability make Purdue +3.5 vs. Alabama at a value play in the Purdue vs. Alabama matchup, per our model.

 

Kansas State -6.5 (-105)

Kansas State -6.5 at -105 odds presents a 3.8% edge, with simulations resulting in a probability of 55%.

 

Cornell vs. Lafayette under 157.5 points (-105)

Our model finds value on under 157.5 points in Cornell vs. Lafayette at -105 odds, supported by an edge of 3.6%.

 

Central Michigan ML (+184)

  • Edge: 3.2%
  • Probability: 38.4%
  • Matchup: Central Michigan vs. South Alabama (11:00AM ET, Thursday) Our model has uncovered value on Central Michigan ML at +184 odds. A 38.4% probability produces a 3.2% edge, making this a strong play for today's men's college basketball action.

 

West Virginia ML (-220)

A 3.2% edge on a 71.9% probability makes West Virginia to win at -220 odds a solid value play in today's Pittsburgh vs. West Virginia matchup.

 

San Jose State vs. Michigan State over 142.5 points (-105)

Our model projects value on over 142.5 points at -105 odds. A 54.2% probability produces a 3.0% edge, making the over the favorable side in Saturday’s matchup.

 

Central Michigan vs. South Alabama over 144.5 points (-105)

Rounding out our top 10 bets, Central Michigan vs. South Alabama over 144.5 points at -105 odds shows a 54% probability and a 2.8% edge.

 

NCAAM best bets summary: Wednesday, 11/12/2025

As of 9:38PM ET, here are our top men's college basketball bets by edge recommended by our model:

Matchup Bet Odds Edge Probability
Southern Illinois vs. Nevada Nevada -10.5 -110 @ FanDuel 2.6% 55%
Southern Illinois vs. Nevada Under 151.5 Points -105 @ FanDuel 2.6% 53.8%
Purdue vs. Alabama Purdue +3.5 -105 @ DraftKings 4.6% 55.8%
California vs. Kansas State Kansas State -6.5 -105 @ FanDuel 3.8% 55%
Cornell vs. Lafayette Under 157.5 Points -105 @ FanDuel 3.6% 54.8%
Central Michigan vs. South Alabama Central Michigan ML +184 @ FanDuel 3.2% 38.4%
Pittsburgh vs. West Virginia West Virginia ML -220 @ BetMGM 3.2% 71.9%
San Jose State vs. Michigan State Over 142.5 Points -105 @ DraftKings 3.0% 54.2%
Central Michigan vs. South Alabama Over 144.5 Points -105 @ DraftKings 2.8% 54%

List of upcoming men's college basketball games to bet on now

Conclusion

Our men's college basketball best bets are locked and loaded for November 12, 2025, featuring plays such as Nevada -10.5 and under 151.5 points also in the Southern Illinois vs. Nevada matchup. Powered by advanced simulations, these picks are here to boost your betting game.

This article, enhanced by AI and automation, aims to deliver accurate college basketball insights quickly, with human oversight ensuring high editorial quality. Our predictions are sourced from current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.

Note: Clicking links to our sportsbook partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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