Men's college basketball picks today: Wednesday's best bets include Quinnipiac vs. Mount St. Mary's play [1/21/2026]

Mount St. Mary's +5.5 (-115)

• Edge: 10.5%
• Probability: 63.9%
• Matchup: Quinnipiac vs. Mount St. Mary's (7:00PM ET, Thursday)

Our model has identified value on Mount St. Mary's +5.5 at -115 odds. A 63.9% probability produces an edge of 10.5%, making this the strongest play for today's men's college basketball slate.

UC Davis +2.5 (-105)

• Edge: 6.5%
• Probability: 57.7%
• Matchup: UC San Diego vs. UC Davis (9:00PM ET, Thursday)

UC Davis +2.5 carries a 6.5% edge and a probability of 57.7% at -105 odds, according to our model.

Louisiana-Lafayette vs. Appalachian State over 125.5 points (-105)

• Edge: 5.7%
• Probability: 56.9%
• Matchup: Louisiana-Lafayette vs. Appalachian State (12:00PM ET, Thursday)

Louisiana-Lafayette vs. Appalachian State over 125.5 points at -105 odds shows a 5.7% edge, supported by a 56.9% probability in simulations.

Merrimack ML (-118)

• Edge: 5.5%
• Probability: 59.6%
• Matchup: Merrimack vs. Iona (7:00PM ET, Thursday)

A 5.5% edge and 59.6% probability make Merrimack at the moneyline at a value play in the Merrimack vs. Iona matchup, per our model.

Towson vs. Elon over 145.5 points (-110)

• Edge: 5.3%
• Probability: 57.7%
• Matchup: Towson vs. Elon (7:00PM ET, Thursday)

Towson vs. Elon over 145.5 points at -110 odds presents a 5.3% edge, with simulations resulting in a probability of 57.7%.

Youngstown State -6.5 (-110)

• Edge: 4.9%
• Probability: 57.3%
• Matchup: Green Bay vs. Youngstown State (6:30PM ET, Thursday)

Our model finds value on Youngstown State -6.5 at -110 odds, supported by an edge of 4.9%.

Southeast Missouri State ML (-250)

• Edge: 4.6%
• Probability: 76%
• Matchup: Arkansas-Little Rock vs. Southeast Missouri State (8:30PM ET, Thursday)

Our model has uncovered value on Southeast Missouri State ML at -250 odds. A 76% probability produces a 4.6% edge, making this a strong play for today's men's college basketball action.

Stony Brook +3.5 (-105)

• Edge: 4.6%
• Probability: 55.8%
• Matchup: Stony Brook vs. Northeastern (7:00PM ET, Thursday)

A 4.6% edge on a 55.8% probability makes Stony Brook +3.5 at -105 odds a solid value play in today's Stony Brook vs. Northeastern matchup.

Campbell +3.5 (-105)

• Edge: 4.6%
• Probability: 55.8%
• Matchup: Campbell vs. Charleston (7:00PM ET, Thursday)

Our model projects value on Campbell +3.5 at -105 odds. A 55.8% probability produces a 4.6% edge, making Campbell the favorable side in Saturday’s matchup.

Youngstown State ML (-285)

• Edge: 4.4%
• Probability: 78.4%
• Matchup: Arkansas-Little Rock vs. Southeast Missouri State (6:30PM ET, Thursday)

Rounding out our top 10 bets, Youngstown State to defeat Green Bay at -285 odds shows a 78.4% probability and a 4.4% edge.

NCAAM best bets summary: Wednesday, 1/21/2026

As of 10:31PM ET, here are our top men's college basketball bets by edge recommended by our model:

Matchup	Bet	Odds	Edge	Probability
Quinnipiac vs. Mount St. Mary's	Mount St. Mary's +5.5	-115 @ DraftKings	10.5%	63.9%
UC San Diego vs. UC Davis	UC Davis +2.5	-105 @ BetMGM	6.5%	57.7%
Louisiana-Lafayette vs. Appalachian State	Over 125.5 Points	-105 @ DraftKings	5.7%	56.9%
Merrimack vs. Iona	Merrimack ML	-118 @ BetMGM	5.5%	59.6%
Towson vs. Elon	Over 145.5 Points	-110 @ FanDuel	5.3%	57.7%
Green Bay vs. Youngstown State	Youngstown State -6.5	-110 @ FanDuel	4.9%	57.3%
Arkansas-Little Rock vs. Southeast Missouri State	Southeast Missouri State ML	-250 @ BetMGM	4.6%	76%
Stony Brook vs. Northeastern	Stony Brook +3.5	-105 @ BetMGM	4.6%	55.8%
Campbell vs. Charleston	Campbell +3.5	-105 @ DraftKings	4.6%	55.8%
Green Bay vs. Youngstown State	Youngstown State ML	-285 @ BetMGM	4.4%	78.4%

List of upcoming men's college basketball games to bet on now

• San Diego State vs. Grand Canyon (11:00PM ET, Wednesday)
• Northwestern vs. USC (11:00PM ET, Wednesday)
• Oregon State vs. Saint Mary's (11:00PM ET, Wednesday)
• Louisiana-Lafayette vs. Appalachian State (12:00PM ET, Thursday)
• Albany vs. Maine (6:00PM ET, Thursday)
• N.J.I.T. vs. UMBC (6:00PM ET, Thursday)
• Binghamton vs. New Hampshire (6:00PM ET, Thursday)
• Vermont vs. Massachusetts-Lowell (6:00PM ET, Thursday)
• Green Bay vs. Youngstown State (6:30PM ET, Thursday)
• Wisconsin vs. Penn State (7:00PM ET, Thursday)

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Conclusion

Our men's college basketball best bets are locked and loaded for January 21, 2026, featuring plays such as Mount St. Mary's +5.5 and UC Davis +2.5. Powered by advanced simulations, these picks are here to boost your betting game.

This article, enhanced by AI and automation, aims to deliver accurate college basketball insights quickly, with human oversight ensuring high editorial quality. Our predictions are grounded in current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.

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