Men's college basketball picks today: Monday's best bets include Santa Clara vs. Xavier play [11/10/2025]

Today’s men's college basketball picks for November 10, 2025 are here, with Santa Clara vs. Xavier and among the top plays identified by our model across Monday’s men's college basketball schedule.

Dimers’ predictive analytics engine runs 24/7, scanning the latest men's college basketball odds to uncover genuine betting edges. The result? Data-backed picks that help Dimers Pro members make smarter decisions.

List of NCAAM picks tonight [11/10, updated 8:04PM ET]

Below, you’ll find today’s best men's college basketball bets, ranked by edge for Monday, November 10, 2025.

Santa Clara +3.5 (-118)

• Edge: 4.3%
• Probability: 58.4%
• Matchup: Santa Clara vs. Xavier (8:30PM ET, Monday)

Our model has identified value on Santa Clara +3.5 at -118 odds. A 58.4% probability produces an edge of 4.3%, making this the strongest play for today's men's college basketball slate.

Louisiana-Lafayette +5.5 vs. Tulane (-110)

• Edge: 4.4%
• Probability: 56.8%
• Matchup: Tulane vs. Louisiana-Lafayette (8:00PM ET, Tuesday)

A 4.4% edge and 56.8% probability make Louisiana-Lafayette +5.5 vs. Tulane at a value play in the Tulane vs. Louisiana-Lafayette matchup, per our model.

Santa Clara +3.5 (-118)

• Edge: 4.3%
• Probability: 58.4%
• Matchup: Santa Clara vs. Xavier (8:30PM ET, Monday)

Santa Clara +3.5 at -118 odds presents a 4.3% edge, with simulations resulting in a probability of 58.4%.

NCAAM best bets summary: Monday, 11/10/2025

As of 8:04PM ET, here is our top men's college basketball bet by edge recommended by our model:

List of upcoming men's college basketball games to bet on now

• Santa Clara vs. Xavier (8:30PM ET, Monday)
• Cleveland State vs. Northwestern (8:30PM ET, Monday)
• Holy Cross vs. Utah (9:00PM ET, Monday)
• Northern Illinois vs. Grand Canyon (9:00PM ET, Monday)
• Southeastern Louisiana vs. Georgia Tech (9:00PM ET, Monday)
• Cal State Fullerton vs. California (10:00PM ET, Monday)
• Iona vs. Kansas City (1:00PM ET, Tuesday)
• Wake Forest vs. Michigan (6:30PM ET, Tuesday)
• Appalachian State vs. Ohio State (6:30PM ET, Tuesday)
• Florida State vs. Florida (7:00PM ET, Tuesday)

Conclusion

Our men's college basketball best bets are locked and loaded for November 10, 2025, featuring plays such as Santa Clara +3.5. Powered by advanced simulations, these picks are here to boost your betting game.

This article, enhanced by AI and automation, aims to deliver accurate college basketball insights quickly, with human oversight ensuring high editorial quality. Our predictions are rooted in current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.

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