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Grizzlies vs. Spurs prediction: San Antonio favored to win Tuesday's NBA game [11/18/2025]

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Written by Jason Bevilacqua

Get Memphis Grizzlies vs San Antonio Spurs predictions for NBA Tuesday.

Memphis Grizzlies-San Antonio Spurs Predictions and Game Preview.
Memphis Grizzlies vs. San Antonio Spurs NBA prediction for Tuesday, November 18, 2025.

The San Antonio Spurs will square off with the Memphis Grizzlies in NBA action at Frost Bank Center on Tuesday, starting at 8:00PM ET.

Based on updated simulations and today’s injury news, Dimers' advanced NBA model projects the Spurs as the most likely winner of the Grizzlies vs. Spurs game.

This prediction follows the latest NBA Injury Report, which suggests the Spurs lineup will feature players like De'Aaron Fox, Devin Vassell and Harrison Barnes, while the Grizzlies will rely on Jaren Jackson, Cedric Coward and Santi Aldama.

This article offers further insights into Tuesday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Grizzlies vs. Spurs prediction: Who will win and cover?

As part of Dimers' NBA predictions coverage—and following a review of recent results—our pregame model has generated moneyline, spread, and over/under probabilities for Tuesday's clash between the Grizzlies and Spurs.

According to our model, the bookmakers have got it right, and the Grizzlies and Spurs each have a 50% chance of covering the spread, while the over/under total of 233.5 points has a 52% chance of staying under.

 

Grizzlies vs. Spurs odds

We have researched the best NBA odds in America for this game, which are listed here:

Bet Type Grizzlies Spurs
Spread +6.5 (-115) -6.5 (-105)
Moneyline +200 -230
Total o233.5 (-118) u233.5 (-110)

All odds are correct at the time of publication and are subject to change.

Grizzlies vs. Spurs picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Spurs -6.5 -105
Moneyline Spurs -230
Total Under 233.5 -110

According to our best NBA bets for Tuesday, the top play to make on this game is Spurs to win.

 

Grizzlies vs. Spurs player props

NBA prop bets are a great way to wager on the Grizzlies vs. Spurs game without necessarily betting on the outcome. We have crunched the numbers to project how each team's leading players will perform at Frost Bank Center.

Jaren Jackson is expected to lead the Grizzlies with 22 points, 5 rebounds and 2 assists, while De'Aaron Fox is projected to have 26 points, 5 rebounds and 8 assists for the Spurs.

Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and more, for every game this season.

Grizzlies prediction

Our model's projected player stats for the Grizzlies are:

Player PTS REB AST 3PM DFS
Jaren Jackson 22 5 2 2 38
Cedric Coward 14 6 4 2 30
Santi Aldama 13 6 3 2 29
Zach Edey 11 9 2 0 30
Vince Williams 11 5 4 2 29

Spurs prediction

Projected points, rebounds, assists and three-pointers made for the Spurs:

Player PTS REB AST 3PM DFS
De'Aaron Fox 26 5 8 2 50
Devin Vassell 17 4 4 3 33
Harrison Barnes 14 4 2 3 27
Keldon Johnson 14 6 2 1 28
J. Champagnie 12 5 2 3 26

Grizzlies vs. Spurs game-day updates and essential details

Tuesday's game between the Spurs and Grizzlies at Frost Bank Center is scheduled to begin at 8:00PM ET.

Conclusion

We predict the Spurs, with a 71% win probability, will likely beat the Grizzlies on Tuesday, with De'Aaron Fox projected for a game-high 50 fantasy points.

AI and automation have enhanced this article to quickly deliver accurate Grizzlies vs. Spurs insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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