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Grizzlies vs. Celtics prediction: Boston favored to win Wednesday's NBA game [11/12/2025]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Memphis Grizzlies vs Boston Celtics predictions for NBA Wednesday.
The Boston Celtics and Memphis Grizzlies will meet in NBA action at TD Garden on Wednesday, starting at 7:30PM ET.
Based on updated simulations and today’s injury news, Dimers' proven NBA model predicts the Celtics as the most likely winner of the Grizzlies vs. Celtics game.
This prediction follows the latest NBA Injury Report, which suggests the Celtics lineup will feature stars like Jaylen Brown, Derrick White and Payton Pritchard, while the Grizzlies will be led by Jaren Jackson, Cedric Coward and Santi Aldama.
This article offers an expanded analysis of Wednesday's matchup, including an expanded look at the predicted score, best bets and player prop picks.
Grizzlies vs. Celtics prediction: Who will win, cover the spread?
Using trusted machine learning and statistical analysis, we have simulated the outcome of Wednesday's NBA matchup between the Grizzlies and Celtics 10,000 times as part of our NBA predictions coverage.
Our independent predictive model currently gives the Celtics a 74% chance of defeating the Grizzlies. Our predicted final score has the Celtics winning 117-109.
According to our model, the Grizzlies (+8.5) have a 54% chance of covering the spread, while the 227.5-point over/under has a 51% chance of going over.
Grizzlies vs. Celtics odds
We have sourced the best NBA odds in America for this game, which are listed here:
| Bet Type | Grizzlies | Celtics |
|---|---|---|
| Spread | +8.5 (-110) | -8.5 (-105) |
| Moneyline | +260 | -310 |
| Total | o227.5 (-110) | u227.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Grizzlies vs. Celtics picks and best bet
After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Grizzlies +8.5 | -110 |
| Moneyline | Celtics | -310 |
| Total | Over 227.5 | -110 |
According to our best NBA bets for Wednesday, the top play to make on this game is Grizzlies +8.5 at the spread.
Grizzlies vs. Celtics player props
Looking for Grizzlies vs. Celtics NBA prop bets? We use the best information available to project how each team's leading players will perform at TD Garden.
Jaren Jackson is expected to lead the Grizzlies with 19 points, 5 rebounds and 2 assists, while Jaylen Brown is projected to have 25 points, 6 rebounds and 5 assists for the Celtics.
Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and more, for every game this season.
Grizzlies prediction
Our model's projected player stats for the Grizzlies are:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| Jaren Jackson | 19 | 5 | 2 | 2 | 33 |
| Cedric Coward | 15 | 7 | 3 | 2 | 33 |
| Santi Aldama | 13 | 6 | 3 | 2 | 29 |
| Cam Spencer | 12 | 3 | 4 | 2 | 26 |
| Jaylen Wells | 11 | 4 | 2 | 2 | 21 |
Celtics prediction
Projected points, rebounds, assists and three-pointers made for the Celtics:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| Jaylen Brown | 25 | 6 | 5 | 2 | 44 |
| Derrick White | 17 | 5 | 6 | 4 | 39 |
| Payton Pritchard | 16 | 4 | 4 | 3 | 32 |
| Anfernee Simons | 16 | 2 | 3 | 3 | 27 |
| Neemias Queta | 9 | 8 | 2 | 0 | 27 |
Grizzlies vs. Celtics game-day updates and essential details
Wednesday's game between the Celtics and Grizzlies at TD Garden is scheduled to start at 7:30PM ET.
- Who: Memphis Grizzlies vs. Boston Celtics
- Date: Wednesday, November 12, 2025
- Time: 7:30PM ET/4:30PM PT
- Venue: TD Garden
Conclusion
We predict the Celtics, with a 74% win probability, will likely beat the Grizzlies on Wednesday, with Jaylen Brown projected for 44 fantasy points.
AI and automation have enhanced this article to quickly deliver accurate Grizzlies vs. Celtics insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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