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UMass vs. Charleston prediction: Why Charleston is favored to win men's college basketball matchup [11/21/2025]
Get UMass vs Charleston predictions for college basketball Friday.

Charleston and UMass will lock horns in men's college basketball action at Virgin Islands Sport & Fitness Center on Friday, with tipoff at 3:00PM ET.
Based on the latest simulations, Dimers' advanced college basketball model projects Charleston as the most likely winner of the UMass vs. Charleston game.
This article offers a closer look at Friday's matchup, including an expanded look at the predicted score, best bets and picks.
UMass vs. Charleston prediction: Who will win and cover?
Using innovative machine learning and data analysis, we have simulated the result of Friday's NCAA basketball game between UMass and Charleston 10,000 times as part of our men's college basketball predictions coverage.
Our independent predictive model gives Charleston a 62% chance of beating Massachusetts. Our predicted final score has Charleston winning 80-76.
According to our model, the bookies have got it right, and Massachusetts and Charleston each have a 50% chance of covering the spread, while the over/under total of 161.5 points has a 54% chance of staying under.
UMass vs. Charleston odds
We have sourced the best Men's College Basketball odds in America for this game, which are listed here:
| Bet Type | UMass | Charleston |
|---|---|---|
| Spread | +3.5 (-105) | -3.5 (-110) |
| Moneyline | +150 | -170 |
| Total | o161.5 (-105) | u161.5 (-110) |
All odds are correct at the time of publication and are subject to change.
UMass vs. Charleston picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Massachusetts +3.5 | -105 |
| Moneyline | Charleston | -170 |
| Total | Under 161.5 | -110 |
According to our men's college basketball best bets, the top play to make on this game is Under 161.5 total points.
UMass vs. Charleston game-day updates and essential details
Friday's men's college basketball game between Charleston and UMass at Virgin Islands Sport & Fitness Center is scheduled to begin at 3:00PM ET.
- Who: Massachusetts vs. Charleston
- Date: Friday, November 21, 2025
- Time: 3:00PM ET/12:00PM PT
- Venue: Virgin Islands Sport & Fitness Center
Conclusion
We predict Charleston, with a 62% win probability, will likely beat Massachusetts on Friday.
AI and automation have enhanced this article to quickly deliver accurate Massachusetts vs. Charleston insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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