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Marquette vs. DePaul prediction: DePaul favored to win men's college basketball matchup [1/16/2026]
Updated: | First published:
Written by Mac Douglass, Senior Editor
Get Marquette vs DePaul predictions for college basketball Friday.
DePaul will face Marquette in men's college basketball action at Wintrust Arena on Friday, starting at 8:30 PM ET.
Based on the latest simulations, Dimers' advanced college basketball model predicts DePaul as the most likely winner of the Marquette vs. DePaul game.
This article offers an expanded analysis of Friday's matchup, including an expanded look at the predicted score, best bets and picks.
Marquette vs. DePaul prediction: Who will win and cover?
Using innovative machine learning and data, we have simulated the outcome of Friday's NCAA basketball matchup between Marquette and DePaul 10,000 times as part of our men's college basketball predictions coverage.
Our famous predictive model currently gives DePaul a 59% chance of beating Marquette. Our predicted final score has DePaul winning 73-71.
According to our model, Marquette (+2.5) has a 51% chance of covering the spread, while the over/under total of 145.5 points has a 52% chance of going over.
Marquette vs. DePaul odds
We have sourced the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Marquette | DePaul |
|---|---|---|
| Spread | +2.5 (-102) | -2.5 (-110) |
| Moneyline | +128 | -148 |
| Total | o145.5 (-105) | u145.5 (-115) |
All odds are correct at the time of publication and are subject to change.
Marquette vs. DePaul picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Marquette +2.5 | -102 |
| Moneyline | DePaul | -148 |
| Total | Over 145.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is Over 145.5 total points.
Marquette vs. DePaul game-day updates and essential details
Friday's men's college basketball game between DePaul and Marquette at Wintrust Arena is scheduled to start at 8:30 PM ET.
- Who: Marquette vs. DePaul
- Date: Friday, January 16, 2026
- Time: 8:30 PM ET/5:30PM PT
- Venue: Wintrust Arena
Conclusion
We predict DePaul, with a 59% win probability, will likely beat Marquette on Friday.
AI and automation have enhanced this article to quickly deliver accurate Marquette vs. DePaul insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.
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