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Marquette vs. Creighton prediction: Why Creighton is favored to win men's college basketball matchup [12/20/2025]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Marquette vs Creighton predictions for college basketball Saturday.
Men's college basketball action continues on Saturday at 8:30 PM ET as Marquette takes on the favored Creighton in men's college basketball action at CHI Health Center Omaha.
Based on updated simulation results, Dimers' advanced college basketball model predicts Creighton as the most likely winner of the Marquette vs. Creighton game.
This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.
Marquette vs. Creighton prediction: Who will win and cover?
Using innovative machine learning and data, we have simulated the result of Saturday's NCAA basketball matchup between Marquette and Creighton 10,000 times as part of our men's college basketball predictions coverage.
Our independent predictive model gives Creighton a 76% chance of defeating Marquette. Our predicted final score has Creighton winning 79-72.
According to our model, Creighton (-6.5) has a 55% chance of covering the spread, while the 151.5-point over/under has an equal 50-50 chance of hitting.
Marquette vs. Creighton odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Marquette | Creighton |
|---|---|---|
| Spread | +6.5 (-105) | -6.5 (-110) |
| Moneyline | +240 | -295 |
| Total | o151.5 (-115) | u151.5 (-105) |
All odds are correct at the time of publication and are subject to change.
Marquette vs. Creighton picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Creighton -6.5 | -110 |
| Moneyline | Creighton | -295 |
| Total | Under 151.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is Creighton -6.5 at the spread.
Marquette vs. Creighton game-day updates and essential details
Saturday's men's college basketball matchup between Creighton and Marquette at CHI Health Center Omaha is scheduled to commence at 8:30 PM ET.
- Who: Marquette vs. Creighton
- Date: Saturday, December 20, 2025
- Time: 8:30 PM ET/5:30PM PT
- Venue: CHI Health Center Omaha
Conclusion
We predict Creighton, with a 76% win probability, will likely beat Marquette on Saturday.
AI and automation have enhanced this article to quickly deliver accurate Marquette vs. Creighton insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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