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Maine vs. Drexel prediction: Drexel favored to win men's college basketball matchup [12/21/2025]

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Written by Jason Bevilacqua

Get Maine vs Drexel predictions for college basketball Sunday.

Maine-Drexel Predictions and Game Preview.
Maine vs. Drexel men's college basketball prediction for Sunday, December 21, 2025.

Drexel and Maine will meet in men's college basketball action at Daskalakis Athletic Center on Sunday, with tipoff at 2:00 PM ET.

Based on updated simulations, Dimers' advanced college basketball model projects Drexel as the most likely winner of the Maine vs. Drexel game.

This article offers a closer look at Sunday's matchup, including an expanded look at the predicted score, best bets and picks.

Maine vs. Drexel prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the result of Sunday's NCAA basketball game between Maine and Drexel 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Drexel an 89% chance of defeating Maine. Our predicted final score has Drexel winning 72-60.

According to our model, Drexel (-10.5) has a 56% chance of covering the spread, while the over/under total of 130.5 points has a 54% chance of going over.

 

Maine vs. Drexel odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

Bet Type Maine Drexel
Spread +10.5 (-105) -10.5 (-108)
Moneyline +470 -600
Total o130.5 (-105) u130.5 (-115)

All odds are correct at the time of publication and are subject to change.

Maine vs. Drexel picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Drexel -10.5 -108
Moneyline Drexel -600
Total Over 130.5 -105

According to our men's college basketball best bets, the top play to make on this game is Drexel -10.5 at the spread.

 

Maine vs. Drexel game-day updates and essential details

Sunday's men's college basketball matchup between Drexel and Maine at Daskalakis Athletic Center is scheduled to commence at 2:00 PM ET.

  • Who: Maine vs. Drexel
  • Date: Sunday, December 21, 2025
  • Time: 2:00 PM ET/11:00AM PT
  • Venue: Daskalakis Athletic Center

Conclusion

We predict Drexel, with an 89% win probability, will likely beat Maine on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Maine vs. Drexel insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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