LSU vs. Vanderbilt prediction: Vanderbilt favored to win men's college basketball matchup [1/10/2026]

Men's college basketball action continues on Saturday at 1:00 PM ET as LSU takes on Vanderbilt in men's college basketball action at Memorial Gymnasium.

Based on the latest simulations, Dimers' advanced college basketball model projects Vanderbilt as the most likely winner of the LSU vs. Vanderbilt game.

This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

LSU vs. Vanderbilt prediction: Who will win and cover?

Using powerful machine learning and statistical analysis, we have simulated the outcome of Saturday's NCAA basketball game between LSU and Vanderbilt 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model currently gives Vanderbilt an 89% chance of defeating LSU. Our predicted final score has Vanderbilt winning 86-72.

According to our model, Vanderbilt (-14.5) has a 52% chance of covering the spread, while the 159.5-point over/under has a 54% chance of staying under.

LSU vs. Vanderbilt odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

LSU vs. Vanderbilt picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: