LSU vs. Duke prediction: LSU favored to win women's college basketball matchup [12/4/2025]

Duke and LSU will lock horns in the women's college basketball at Cameron Indoor Stadium on Thursday, starting at 9:00PM ET.

Based on the latest simulations, Dimers' new women's basketball model predicts LSU as the most likely winner of the LSU vs. Duke game.

This article offers an expanded analysis of Thursday's matchup, including best bets and picks.

LSU vs. Duke prediction: Who will win?

Using trusted machine learning and data, we have simulated the outcome of Thursday's women's basketball game between LSU and Duke 10,000 times as part of our women's college basketball predictions coverage.

Our independent predictive model currently gives LSU a 75% chance of beating Duke.

According to our model, the over/under total of 148.5 points has a 63% chance of staying under.

LSU vs. Duke odds

We have sourced the best women's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

LSU vs. Duke picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: