Loyola (MD) vs. George Mason prediction: George Mason favored to win men's college basketball matchup [12/21/2025]

George Mason will face Loyola (MD) in men's college basketball action at EagleBank Arena on Sunday, starting at 2:00 PM ET.

Based on the latest simulation results, Dimers' proven college basketball model predicts George Mason as the most likely winner of the Loyola (MD) vs. George Mason game.

This article offers an expanded analysis of Sunday's matchup, including an expanded look at the predicted score, best bets and picks.

Loyola (MD) vs. George Mason prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the outcome of Sunday's NCAA basketball game between Loyola (MD) and George Mason 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model currently gives George Mason a 98% chance of beating Loyola (MD). Our predicted final score has George Mason winning 84-61.

According to our model, the bookmakers have got it right, and Loyola (MD) and George Mason each have a 50% chance of covering the spread, while the over/under total of 146.5 points has a 55% chance of staying under.

Loyola (MD) vs. George Mason odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Loyola (MD) vs. George Mason picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: