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Loyola (MD) vs. George Mason prediction: George Mason favored to win men's college basketball matchup [12/21/2025]

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Written by Jason Bevilacqua

Get Loyola (MD) vs George Mason predictions for college basketball Sunday.

Loyola (MD)-George Mason Predictions and Game Preview.
Loyola (MD) vs. George Mason men's college basketball prediction for Sunday, December 21, 2025.

George Mason will take on Loyola (MD) in men's college basketball action at EagleBank Arena on Sunday, starting at 2:00 PM ET.

Based on the latest simulation results, Dimers' proven college basketball model predicts George Mason as the most likely winner of the Loyola (MD) vs. George Mason game.

This article offers an expanded analysis of Sunday's matchup, including an expanded look at the predicted score, best bets and picks.

Loyola (MD) vs. George Mason prediction: Who will win and cover?

Using trusted machine learning and data analysis, we have simulated the result of Sunday's NCAA basketball matchup between Loyola (MD) and George Mason 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model currently gives George Mason a 98% chance of beating Loyola (MD). Our predicted final score has George Mason winning 84-61.

According to our model, the bookmakers have got it right, and Loyola (MD) and George Mason each have a 50% chance of covering the spread, while the 145.5-point over/under has a 52% chance of staying under.

 

Loyola (MD) vs. George Mason odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

Bet Type Loyola (MD) George Mason
Spread +23.5 (-108) -23.5 (-110)
Moneyline +3000 -10000
Total o145.5 (-112) u145.5 (-105)

All odds are correct at the time of publication and are subject to change.

Loyola (MD) vs. George Mason picks and best bet

After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Loyola (MD) +23.5 -108
Moneyline Loyola (MD) +3000
Total Under 145.5 -105

According to our men's college basketball best bets, the top play to make on this game is Under 145.5 total points.

 

Loyola (MD) vs. George Mason game-day updates and essential details

Sunday's men's college basketball game between George Mason and Loyola (MD) at EagleBank Arena is scheduled to start at 2:00 PM ET.

  • Who: Loyola (MD) vs. George Mason
  • Date: Sunday, December 21, 2025
  • Time: 2:00 PM ET/11:00AM PT
  • Venue: EagleBank Arena

Conclusion

We predict George Mason, with a 98% win probability, will likely beat Loyola (MD) on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Loyola (MD) vs. George Mason insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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