Loyola Marymount vs. Santa Clara prediction: Santa Clara favored to win men's college basketball matchup [1/10/2026]

Santa Clara and Loyola Marymount are scheduled to meet in men's college basketball action at Leavey Center on Saturday, starting at 10:00 PM ET.

Based on the latest simulation results, Dimers' advanced college basketball model projects Santa Clara as the most likely winner of the Loyola Marymount vs. Santa Clara game.

This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Loyola Marymount vs. Santa Clara prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the outcome of Saturday's NCAA basketball matchup between Loyola Marymount and Santa Clara 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model currently gives Santa Clara an 86% chance of beating Loyola Marymount. Our predicted final score has Santa Clara winning 81-69.

According to our model, Santa Clara (-11.5) has a 54% chance of covering the spread, while the over/under total of 152.5 points has a 55% chance of staying under.

Loyola Marymount vs. Santa Clara odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Loyola Marymount vs. Santa Clara picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: