Loyola Chicago vs. St. Bonaventure prediction: St. Bonaventure favored to win men's college basketball matchup [1/20/2026]

St. Bonaventure will square off with Loyola Chicago in men's college basketball action at Reilly Center on Tuesday, beginning at 7:00 PM ET.

Based on updated simulation results, Dimers' advanced college basketball model predicts St. Bonaventure as the most likely winner of the Loyola Chicago vs. St. Bonaventure game.

This article offers further insights into Tuesday's matchup, including an expanded look at the predicted score, best bets and picks.

Loyola Chicago vs. St. Bonaventure prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the result of Tuesday's NCAA basketball matchup between Loyola Chicago and St. Bonaventure 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model gives St. Bonaventure an 86% chance of defeating Loyola Chicago. Our predicted final score has St. Bonaventure winning 79-67.

According to our model, the bookies have got it right, and Loyola Chicago and St. Bonaventure each have a 50% chance of covering the spread, while the 146.5-point over/under has a 51% chance of going over.

Loyola Chicago vs. St. Bonaventure odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Loyola Chicago vs. St. Bonaventure picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: