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Loyola Chicago vs. UConn prediction: Why Connecticut is favored to win women's college basketball matchup [11/12/2025]

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Written by Ryan Leaver

Get Loyola Chicago vs UConn predictions for college basketball Wednesday.

Loyola Chicago-UConn Predictions and Game Preview.
Loyola Chicago vs. UConn women's college basketball prediction for Wednesday, November 12, 2025.

Women's college basketball action continues on Wednesday at 7:30PM ET as Loyola Chicago takes on UConn at Harry A. Gampel Pavilion.

Based on updated simulations, Dimers' new women's basketball model predicts Connecticut as the most likely winner of the Loyola Chicago vs. UConn game.

This article offers a closer look at Wednesday's matchup, including best bets and picks.

Loyola Chicago vs. UConn prediction: Who will win?

Using innovative machine learning and statistical analysis, we have simulated the result of Wednesday's women's basketball matchup between Loyola Chicago and UConn 10,000 times as part of our women's college basketball predictions coverage.

Our leading predictive model currently gives Connecticut a 99% chance of defeating Loyola Chicago.

According to our model, the 128.5-point over/under has a 51% chance of staying under.

 

Loyola Chicago vs. UConn odds

We have researched the best women's college basketball odds in America for this game, which are listed here:

Bet Type Loyola Chicago UConn
Spread +54.5 (-110) -54.5 (-110)
Total o128.5 (-110) u128.5 (-110)

All odds are correct at the time of publication and are subject to change.

Loyola Chicago vs. UConn picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Connecticut -54.5 -110
Total Under 128.5 -110

According to our women's college basketball best bets, the top play to make on this game is Connecticut -54.5.

 

Loyola Chicago vs. UConn game-day updates and essential details

Wednesday's women's basketball game between UConn and Loyola Chicago at Harry A. Gampel Pavilion is scheduled to start at 7:30PM ET.

  • Who: Loyola Chicago vs. Connecticut
  • Date: Wednesday, November 12, 2025
  • Time: 7:30PM ET/4:30PM PT
  • Venue: Harry A. Gampel Pavilion

Conclusion

We predict Connecticut, with a 99% win probability, will likely beat Loyola Chicago on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Loyola Chicago vs. Connecticut insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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