Louisiana-Monroe vs. Southern Miss prediction: Southern Miss favored to win men's college basketball matchup [1/10/2026]

Southern Miss will square off with Louisiana-Monroe in men's college basketball action at Reed Green Coliseum on Saturday, starting at 3:00 PM ET.

Based on updated simulations, Dimers' proven college basketball model predicts Southern Miss as the most likely winner of the Louisiana-Monroe vs. Southern Miss game.

This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Louisiana-Monroe vs. Southern Miss prediction: Who will win and cover?

Using trusted machine learning and data analysis, we have simulated the result of Saturday's NCAA basketball game between Louisiana-Monroe and Southern Miss 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model gives Southern Miss an 88% chance of beating Louisiana-Monroe. Our predicted final score has Southern Miss winning 84-71.

According to our model, Louisiana-Monroe (+14.5) has a 53% chance of covering the spread, while the 155.5-point over/under has an equal 50-50 chance of hitting.

Louisiana-Monroe vs. Southern Miss odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Louisiana-Monroe vs. Southern Miss picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: