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Rams vs. Seahawks prediction: Seattle favored to win ‘TNF’ Week 16 [2025]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Get Los Angeles Rams vs Seattle Seahawks predictions for NFL Thursday.
The Seattle Seahawks will square off with the Los Angeles Rams in NFL Week 16 action at Lumen Field on Thursday, beginning at 8:15 PM ET.
Based on updated simulations, Dimers' proven NFL model predicts the Seahawks as the most likely winner of the Rams vs. Seahawks game.
This article offers an expanded analysis of this week's matchup, including projected touchdown scorers, best bets and player prop picks.
Rams vs. Seahawks prediction: Who will win ‘Thursday Night Football’?
Since our Rams-Seahawks predictions earlier in the week, we have simulated the outcome of Thursday's NFL matchup between the Rams and Seahawks 10,000 times as part of our NFL predictions coverage.
Our leading predictive model gives the Seahawks a 55% chance of defeating the Rams in Week 16 of the NFL season. Our predicted final score has the Seahawks winning 22-20.
According to our model, the bookmakers have got it right, and the Rams and Seahawks each have a 50% chance of covering the spread, while the 42.5-point over/under has a 54% chance of going over.
To see win probabilities for every matchup this week, check out our expert NFL Week 16 straight up picks.
Rams vs. Seahawks odds
We have researched the best NFL odds in America for this game, which are listed here:
| Bet Type | Rams | Seahawks |
|---|---|---|
| Spread | +1.5 (-102) | -1.5 (-102) |
| Moneyline | +114 | -130 |
| Total | o42.5 (-102) | u42.5 (-105) |
All odds are correct at the time of publication and are subject to change.
Rams vs. Seahawks picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Rams +1.5 | -102 |
| Moneyline | Seahawks | -130 |
| Total | Over 42.5 | -102 |
According to our NFL best bets, the top play to make on this game is Over 42.5 total points.
Rams vs. Seahawks TD scorers
Who will score a touchdown in Rams vs. Seahawks?
According to our list of touchdown scorer predictions for TNF, Kyren Williams is most likely to score an anytime TD in Rams vs. Seahawks.
Our projections give Williams a 44.0% chance of scoring a TD at Lumen Field, while the wide receiver is a 10.4% chance of scoring the first touchdown the game.
Anytime touchdown scorer predictions
Los Angeles Rams
| Player | Anytime TD Probability |
|---|---|
| Kyren Williams (RB) | 44.0% |
| Puka Nacua (WR) | 40.1% |
| Colby Parkinson (TE) | 30.6% |
| Blake Corum (RB) | 28.1% |
| Terrance Ferguson (TE) | 14.7% |
Seattle Seahawks
| Player | Anytime TD Probability |
|---|---|
| Jaxon Smith-Njigba (WR) | 41.9% |
| Zach Charbonnet (RB) | 34.2% |
| Kenneth Walker (RB) | 32.3% |
| AJ Barner (TE) | 26.9% |
| Rashid Shaheed (WR) | 21.9% |
First touchdown scorer predictions
Los Angeles Rams
| Player | First TD Probability |
|---|---|
| Kyren Williams (RB) | 10.4% |
| Puka Nacua (WR) | 9.1% |
| Colby Parkinson (TE) | 6.5% |
| Blake Corum (RB) | 5.9% |
| Terrance Ferguson (TE) | 2.8% |
Seattle Seahawks
| Player | First TD Probability |
|---|---|
| Jaxon Smith-Njigba (WR) | 10.6% |
| Zach Charbonnet (RB) | 8.2% |
| Kenneth Walker (RB) | 7.6% |
| AJ Barner (TE) | 6.1% |
| Rashid Shaheed (WR) | 4.8% |
Rams vs Seahawks player props
Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Rams and Seahawks. Head to our NFL player projections page now to access a full list of player prop projections for every offensive player in this matchup and all other Week 16 games.
Quarterbacks
Of the starting quarterbacks, the Rams' Matthew Stafford is projected for 243 passing yards, while the Seahawks' Sam Darnold is expected to throw for 228 yards.
| Player | Proj. Pass Yards |
|---|---|
| Matthew Stafford (LA) | 243 |
| Sam Darnold (SEA) | 228 |
Rams rushing
| Player | Proj. Rush Yards |
|---|---|
| Kyren Williams | 62 |
| Blake Corum | 44 |
| Puka Nacua | 4 |
Seahawks rushing
| Player | Proj. Rush Yards |
|---|---|
| Kenneth Walker | 50 |
| Zach Charbonnet | 37 |
| Sam Darnold | 7 |
Rams receiving
| Player | Proj. Rec. Yards |
|---|---|
| Puka Nacua | 95 |
| Colby Parkinson | 41 |
| Terrance Ferguson | 26 |
| Konata Mumpfield | 20 |
| Tutu Atwell | 19 |
Seahawks receiving
| Player | Proj. Rec. Yards |
|---|---|
| Jaxon Smith-Njigba | 92 |
| Rashid Shaheed | 41 |
| Cooper Kupp | 38 |
| AJ Barner | 34 |
| Kenneth Walker | 15 |
Rams vs. Seahawks game-day updates and essential details
The NFL Week 16 action between the Seahawks and Rams at Lumen Field is scheduled to start at 8:15 PM ET.
- Who: Los Angeles Rams vs. Seattle Seahawks
- Date: Thursday, December 18, 2025
- Time: 8:15 PM ET/5:15PM PT
- Venue: Lumen Field
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Conclusion
We predict the Seahawks, with a 55% win probability, will likely beat the Rams in Week 16 of the NFL season.
AI and automation have enhanced this article to quickly deliver accurate Rams vs. Seahawks insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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