Lakers vs. Grizzlies prediction: Lakers to win, Luka Doncic projected for big game in Friday's NBA matchup [10/31/2025]

The Memphis Grizzlies and Los Angeles Lakers will meet in NBA action at FedExForum on Friday, starting at 9:30PM ET.

Based on updated simulation results and today’s injury updates, Dimers' proven NBA model predicts the Lakers as the most likely winner of the Lakers vs. Grizzlies game.

This prediction follows the latest NBA Injury Report, which suggests the Grizzlies lineup will feature stars like Ja Morant, Jaren Jackson and Cedric Coward, while the Lakers will be led by Luka Doncic, Austin Reaves and Deandre Ayton.

LeBron James will not be on the court, with the superstar out for this one.

This article offers further insights into Friday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Lakers vs. Grizzlies prediction: Who will win, cover the spread?

Using trusted machine learning and statistical analysis, we have simulated the result of Friday's NBA game between the Lakers and Grizzlies 10,000 times as part of our NBA predictions coverage.

Our independent predictive model currently gives the Lakers a 60% chance of defeating the Grizzlies. Our predicted final score has the Lakers winning 119-116.

According to our model, the Lakers (-2) have a 51% chance of covering the spread, while the over/under total of 238.5 points has a 55% chance of staying under.

Lakers vs. Grizzlies odds

We have researched the best NBA odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Lakers vs. Grizzlies picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our best NBA bets for Friday, the top play to make on this game is Lakers to win.

Lakers vs. Grizzlies player props

NBA prop bets are an enjoyable way to wager on Friday's Lakers vs. Grizzlies game without necessarily betting on the outcome. We use the best information available to project how each team's leading players will perform at FedExForum.

Luka Doncic is expected to lead the Lakers with 29 points, 7 rebounds and 7 assists, while Ja Morant is projected to have 24 points, 4 rebounds and 8 assists for the Grizzlies.

Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and more, for every game this season.

Lakers prediction

Our model's projected player stats for the Lakers are:

Grizzlies prediction

Projected points, rebounds, assists and three-pointers made for the Grizzlies:

Lakers vs. Grizzlies game-day updates and essential details

Friday's game between the Grizzlies and Lakers at FedExForum is scheduled to commence at 9:30PM ET.

• Who: Los Angeles Lakers vs. Memphis Grizzlies
• Date: Friday, October 31, 2025
• Time: 9:30PM ET/6:30PM PT
• Venue: FedExForum

Conclusion

We predict the Lakers, with a 60% win probability, will likely beat the Grizzlies on Friday.

AI and automation have enhanced this article to quickly deliver accurate Lakers vs. Grizzlies insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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