Lorenzo Musetti vs. Holger Rune Prediction, Odds, Picks for French Open 2025

Lorenzo Musetti and Holger Rune will lock horns in the fourth round of the French Open 2025 on Sunday.

Based on updated simulation results, Dimers' proven tennis model (see Dimers Pro for full access) predicts Lorenzo Musetti as the most likely winner of the match.

"Using the most recent data, we ran 10,000 simulations of Sunday's Musetti-Rune match," said Dimers data analyst Greg Butyn.

"After accounting for recent updates and other variables, our prediction shows Lorenzo Musetti with a win probability of 63%, while Holger Rune has 37%."

For further insights into Sunday's match, including best bets and picks, visit our interactive Musetti vs. Rune predictions page.

Musetti vs. Rune Prediction: Who Will Win and Advance to the Quarterfinals?

Using innovative machine learning and data, we have simulated the result of Sunday's Musetti-Rune men's singles match 10,000 times as part of our tennis predictions coverage.

Our independent predictive model gives Musetti a 63% chance of defeating Rune in the French Open 2025.

Additionally, Musetti has a 58% chance of winning the first set, according to our model.

For more insights into the growing popularity of betting on the sport, check out our comprehensive analysis of tennis' rise in the U.S. sports betting market.

Lorenzo Musetti vs. Holger Rune Odds

We have researched the most up-to-date betting odds in America for this match, which are listed here:

Bet Type	Musetti	Rune
Moneyline	-227	+175
First Set	-164	+130

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Musetti vs. Rune Picks and Best Bets

Our model's biggest edge in today's Musetti vs. Rune match is on the moneyline.

Our expert predictions, aligned with the current odds, reveal the best tennis picks and tennis best bets for every tournament throughout the year.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Musetti vs. Rune Updates and Essential Details

The French Open 2025 match between Lorenzo Musetti and Holger Rune is scheduled to begin on Sunday at 2:15PM ET.

• Who: Lorenzo Musetti vs. Holger Rune
• Date: Sunday, June 1, 2025
• Approx. Time: 2:15PM ET/11:15AM PT
• Tournament: French Open Men's Singles 2025
• Round: Fourth round

All dates and times mentioned in this article are United States Eastern Time unless otherwise stated.

Dimers.com's full preview of Sunday's Musetti vs. Rune match includes our prediction, picks and the latest betting odds.

Before making any Lorenzo Musetti vs. Holger Rune picks, be sure to check out the latest tennis predictions and betting advice from Dimers Pro.

Key Tennis Betting Guides and Insights

• Learn how to bet on tennis and understand how tennis odds work
• Explore where sports odds come from and how they’re applied to tennis matches
• Stay informed with guides on where online sports betting is currently legal and which states could legalize next
• Improve your chances with proven sports betting strategies that apply to tennis and more

Conclusion

We predict Lorenzo Musetti, with a 63% win probability, will likely beat Holger Rune at the French Open 2025.

AI and automation have enhanced this article to quickly deliver accurate Musetti vs. Rune insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on Tennis

Keep up with the latest tennis betting news and parlay picks throughout the year. Plus, Dimers' ATP and WTA world rankings showcase our in-house approach to accurately ranking every men's and women's player in the world.