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LIU vs. Illinois prediction: Why Illinois is favored to win men's college basketball matchup [11/22/2025]

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Written by Dave Garofolo

Get LIU vs Illinois predictions for college basketball Saturday.

LIU-Illinois Predictions and Game Preview.
LIU vs. Illinois men's college basketball prediction for Saturday, November 22, 2025.

Illinois will square off with LIU in men's college basketball action at State Farm Center on Saturday, starting at 2:00PM ET.

Based on the latest simulation results, Dimers' proven college basketball model predicts Illinois as the most likely winner of the LIU vs. Illinois game.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

LIU vs. Illinois prediction: Who will win and cover?

Using trusted machine learning and data analysis, we have simulated the result of Saturday's NCAA basketball matchup between LIU and Illinois 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model gives Illinois a 99% chance of defeating LIU. Our predicted final score has Illinois winning 96-65.

According to our model, LIU (+33.5) has a 54% chance of covering the spread, while the over/under total of 162.5 points has a 51% chance of staying under.

 

LIU vs. Illinois odds

We have sourced the best Men's College Basketball odds in America for this game, which are listed here:

Bet Type LIU Illinois
Spread +33.5 (-104) -33.5 (-118)
Moneyline +8000 -10000
Total o162.5 (-110) u162.5 (-110)

All odds are correct at the time of publication and are subject to change.

LIU vs. Illinois picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread LIU +33.5 -104
Moneyline LIU +8000
Total Under 162.5 -110

According to our men's college basketball best bets, the top play to make on this game is LIU +33.5 at the spread.

 

LIU vs. Illinois game-day updates and essential details

Saturday's men's college basketball action between Illinois and LIU at State Farm Center is scheduled to commence at 2:00PM ET.

  • Who: LIU vs. Illinois
  • Date: Saturday, November 22, 2025
  • Time: 2:00PM ET/11:00AM PT
  • Venue: State Farm Center

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Conclusion

We predict Illinois, with a 99% win probability, will likely beat LIU on Saturday.

AI and automation have enhanced this article to quickly deliver accurate LIU vs. Illinois insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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