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Lipscomb vs. Duke prediction: Duke favored to win men's college basketball matchup [12/16/2025]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Lipscomb vs Duke predictions for college basketball Tuesday.
Duke and Lipscomb are scheduled to meet in men's college basketball action at Cameron Indoor Stadium on Tuesday, starting at 6:00 PM ET.
Based on updated simulation results, Dimers' proven college basketball model projects Duke as the most likely winner of the Lipscomb vs. Duke game.
This article offers an expanded analysis of Tuesday's matchup, including an expanded look at the predicted score, best bets and picks.
Lipscomb vs. Duke prediction: Who will win and cover?
Using powerful machine learning and statistical analysis, we have simulated the result of Tuesday's NCAA basketball game between Lipscomb and Duke 10,000 times as part of our men's college basketball predictions coverage.
Our famous predictive model currently gives Duke a 99% chance of beating Lipscomb. Our predicted final score has Duke winning 90-62.
According to our model, Lipscomb (+31.5) has a 54% chance of covering the spread, while the 151.5-point over/under has a 53% chance of going over.
Lipscomb vs. Duke odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Lipscomb | Duke |
|---|---|---|
| Spread | +31.5 (-105) | -31.5 (-115) |
| Moneyline | +6500 | -100000 |
| Total | o151.5 (-105) | u151.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Lipscomb vs. Duke picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Lipscomb +31.5 | -105 |
| Moneyline | Lipscomb | +6500 |
| Total | Over 151.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is Lipscomb +31.5 at the spread.
Lipscomb vs. Duke game-day updates and essential details
Tuesday's men's college basketball matchup between Duke and Lipscomb at Cameron Indoor Stadium is scheduled to commence at 6:00 PM ET.
- Who: Lipscomb vs. Duke
- Date: Tuesday, December 16, 2025
- Time: 6:00 PM ET/3:00PM PT
- Venue: Cameron Indoor Stadium
Conclusion
We predict Duke, with a 99% win probability, will likely beat Lipscomb on Tuesday.
AI and automation have enhanced this article to quickly deliver accurate Lipscomb vs. Duke insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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