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La Salle vs. Michigan prediction: Why Michigan is favored to win men's college basketball matchup [12/21/2025]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Get La Salle vs Michigan predictions for college basketball Sunday.
Michigan will take on La Salle in men's college basketball action at Crisler Center on Sunday, starting at 4:00 PM ET.
Based on updated simulation results, Dimers' proven college basketball model predicts Michigan as the most likely winner of the La Salle vs. Michigan game.
This article offers further insights into Sunday's matchup, including an expanded look at the predicted score, best bets and picks.
La Salle vs. Michigan prediction: Who will win and cover?
Using trusted machine learning and data, we have simulated the result of Sunday's NCAA basketball matchup between La Salle and Michigan 10,000 times as part of our men's college basketball predictions coverage.
Our famous predictive model gives Michigan a 99% chance of beating La Salle. Our predicted final score has Michigan winning 93-61.
According to our model, La Salle (+39.5) has a 59% chance of covering the spread, while the 153.5-point over/under has a 52% chance of going over.
La Salle vs. Michigan odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | La Salle | Michigan |
|---|---|---|
| Spread | +39.5 (-110) | -39.5 (-108) |
| Moneyline | +8000 | -100000 |
| Total | o153.5 (-108) | u153.5 (-110) |
All odds are correct at the time of publication and are subject to change.
La Salle vs. Michigan picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | La Salle +39.5 | -110 |
| Moneyline | La Salle | +8000 |
| Total | Over 153.5 | -108 |
According to our men's college basketball best bets, the top play to make on this game is La Salle +39.5 at the spread.
La Salle vs. Michigan game-day updates and essential details
Sunday's men's college basketball action between Michigan and La Salle at Crisler Center is scheduled to start at 4:00 PM ET.
- Who: La Salle vs. Michigan
- Date: Sunday, December 21, 2025
- Time: 4:00 PM ET/1:00PM PT
- Venue: Crisler Center
Conclusion
We predict Michigan, with a 99% win probability, will likely beat La Salle on Sunday.
AI and automation have enhanced this article to quickly deliver accurate La Salle vs. Michigan insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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