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La Salle vs. Duquesne prediction: Duquesne favored to win men's college basketball matchup [2/18/2026]
Updated: | First published:
Written by Mac Douglass, Senior Editor
Get La Salle vs Duquesne predictions for college basketball Wednesday.
Duquesne will face La Salle in men's college basketball action at UPMC Cooper Fieldhouse on Wednesday, beginning at 7:00 PM ET.
Based on updated simulation results, Dimers' advanced college basketball model projects Duquesne as the most likely winner of the La Salle vs. Duquesne game.
This article offers a closer look at Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.
La Salle vs. Duquesne prediction: Who will win and cover?
Using powerful machine learning and data, we have simulated the outcome of Wednesday's NCAA basketball game between La Salle and Duquesne 10,000 times as part of our men's college basketball predictions coverage.
Our famous predictive model currently gives Duquesne an 86% chance of beating La Salle. Our predicted final score has Duquesne winning 80-68.
According to our model, the bookmakers have got it right, and La Salle and Duquesne each have a 50% chance of covering the spread, while the over/under total of 145.5 points has a 54% chance of going over.
La Salle vs. Duquesne odds
We have sourced the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | La Salle | Duquesne |
|---|---|---|
| Spread | +11.5 (-115) | -11.5 (-104) |
| Moneyline | +520 | -700 |
| Total | o145.5 (-110) | u145.5 (-105) |
All odds are correct at the time of publication and are subject to change.
La Salle vs. Duquesne picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Duquesne -11.5 | -104 |
| Moneyline | Duquesne | -700 |
| Total | Over 145.5 | -110 |
According to our men's college basketball best bets, the top play to make on this game is Over 145.5 total points.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
La Salle vs. Duquesne game-day updates and essential details
Wednesday's men's college basketball matchup between Duquesne and La Salle at UPMC Cooper Fieldhouse is scheduled to begin at 7:00 PM ET.
- Who: La Salle vs. Duquesne
- Date: Wednesday, February 18, 2026
- Time: 7:00 PM ET/4:00PM PT
- Venue: UPMC Cooper Fieldhouse
Conclusion
We predict Duquesne, with an 86% win probability, will likely beat La Salle on Wednesday.
AI and automation have enhanced this article to quickly deliver accurate La Salle vs. Duquesne insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.
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