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Kansas vs. Iowa State prediction: Why Iowa State is favored to win women's college basketball matchup [12/21/2025]
Get Kansas vs Iowa State predictions for college basketball Sunday.

Iowa State and Kansas will lock horns in the women's college basketball at James H. Hilton Coliseum on Sunday, starting at 1:00 PM ET.
Based on the latest simulation results, Dimers' new women's basketball model projects Iowa State as the most likely winner of the Kansas vs. Iowa State game.
This article offers a closer look at Sunday's matchup, including best bets and picks.
Kansas vs. Iowa State prediction: Who will win?
Using trusted machine learning and data, we have simulated the result of Sunday's women's basketball game between Kansas and Iowa State 10,000 times as part of our women's college basketball predictions coverage.
Our independent predictive model currently gives Iowa State a 95% chance of beating Kansas.
According to our model, the 147.5-point over/under has a 55% chance of staying under.
Kansas vs. Iowa State odds
We have researched the best women's college basketball odds in America for this game, which are listed here:
| Bet Type | Kansas | Iowa State |
|---|---|---|
| Spread | +19.5 (-110) | -19.5 (-110) |
| Moneyline | +1600 | -3571 |
| Total | o147.5 (-110) | u147.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Kansas vs. Iowa State picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Kansas +19.5 | -110 |
| Moneyline | Kansas | +1600 |
| Total | Under 147.5 | -110 |
According to our women's college basketball best bets, the top play to make on this game is Under 147.5 total points.
Kansas vs. Iowa State game-day updates and essential details
Sunday's women's basketball matchup between Iowa State and Kansas at James H. Hilton Coliseum is scheduled to start at 1:00 PM ET.
- Who: Kansas vs. Iowa State
- Date: Sunday, December 21, 2025
- Time: 1:00 PM ET/10:00AM PT
- Venue: James H. Hilton Coliseum
Conclusion
We predict Iowa State, with a 95% win probability, will likely beat Kansas on Sunday.
AI and automation have enhanced this article to quickly deliver accurate Kansas vs. Iowa State insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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