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Kansas vs. Duke prediction: Duke favored to win men's college basketball matchup [11/18/2025]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Kansas vs Duke predictions for college basketball Tuesday.
Duke will square off with Kansas in men's college basketball action at Madison Square Garden on Tuesday, commencing at 9:00PM ET.
Based on the latest simulation results, Dimers' advanced college basketball model projects Duke as the most likely winner of the Kansas vs. Duke game.
This article offers further insights into Tuesday's matchup, including an expanded look at the predicted score, best bets and picks.
Kansas vs. Duke prediction: Who will win and cover?
Using powerful machine learning and data, we have simulated the outcome of Tuesday's NCAA basketball game between Kansas and Duke 10,000 times as part of our men's college basketball predictions coverage.
Our leading predictive model currently gives Duke an 86% chance of defeating Kansas. Our predicted final score has Duke winning 82-70.
According to our model, Duke (-10.5) has a 56% chance of covering the spread, while the over/under total of 148.5 points has a 55% chance of going over.
Kansas vs. Duke odds
We have researched the best Men's College Basketball odds in America for this game, which are listed here:
| Bet Type | Kansas | Duke |
|---|---|---|
| Spread | +10.5 (-102) | -10.5 (-120) |
| Moneyline | +550 | -670 |
| Total | o148.5 (-105) | u148.5 (-114) |
All odds are correct at the time of publication and are subject to change.
Kansas vs. Duke picks and best bet
After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Duke -10.5 | -120 |
| Moneyline | Duke | -670 |
| Total | Over 148.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is Over 148.5 total points.
Kansas vs. Duke game-day updates and essential details
Tuesday's men's college basketball matchup between Duke and Kansas at Madison Square Garden is scheduled to start at 9:00PM ET.
- Who: Kansas vs. Duke
- Date: Tuesday, November 18, 2025
- Time: 9:00PM ET/6:00PM PT
- Venue: Madison Square Garden
Conclusion
We predict Duke, with an 86% win probability, will likely beat Kansas on Tuesday.
AI and automation have enhanced this article to quickly deliver accurate Kansas vs. Duke insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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