Jackson State vs. Louisville prediction: Louisville favored to win men's college basketball matchup [11/6/2025]

Louisville will square off with Jackson State in men's college basketball action at KFC Yum! Center on Thursday, commencing at 7:00PM ET.

Based on the latest simulations, Dimers' advanced college basketball model predicts Louisville as the most likely winner of the Jackson State vs. Louisville game.

This article offers a closer look at Thursday's matchup, including an expanded look at the predicted score, best bets and picks.

Jackson State vs. Louisville prediction: Who will win, cover the spread?

Using powerful machine learning and data analysis, we have simulated the result of Thursday's NCAA basketball game between Jackson State and Louisville 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model gives Louisville a 99% chance of beating Jackson State. Our predicted final score has Louisville winning 94-65.

According to our model, Jackson State (+35.5) has a 57% chance of covering the spread, while the 161.5-point over/under has a 52% chance of staying under.

Jackson State vs. Louisville odds

We have sourced the best Men's College Basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Jackson State vs. Louisville picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our men's college basketball best bets, the top play to make on this game is Jackson State +35.5 at the spread.

Jackson State vs. Louisville game-day updates and essential details

Thursday's men's college basketball action between Louisville and Jackson State at KFC Yum! Center is scheduled to start at 7:00PM ET.

• Who: Jackson State vs. Louisville
• Date: Thursday, November 6, 2025
• Time: 7:00PM ET/4:00PM PT
• Venue: KFC Yum! Center

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Conclusion

We predict Louisville, with a 99% win probability, will likely beat Jackson State on Thursday.

AI and automation have enhanced this article to quickly deliver accurate Jackson State vs. Louisville insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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