IUPUI vs. Northwestern prediction: Northwestern favored to win women's college basketball matchup [11/5/2025]

Northwestern and IUPUI will lock horns in the women's college basketball at Welsh-Ryan Arena on Wednesday, starting at 8:00PM ET.

Based on updated simulation results, Dimers' new women's college basketball model projects Northwestern as the most likely winner of the IUPUI vs. Northwestern game.

This article offers an expanded analysis of Wednesday's matchup, including best bets and picks.

IUPUI vs. Northwestern prediction: Who will win?

Using innovative machine learning and data analysis, we have simulated the result of Wednesday's women's college basketball matchup between IUPUI and Northwestern 10,000 times as part of our women's college basketball predictions coverage.

Our leading predictive model gives Northwestern a 96% chance of beating IUPUI.

According to our model, the over/under total of 141.5 points has a 54% chance of going over.

IUPUI vs. Northwestern odds

We have researched the best women's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

IUPUI vs. Northwestern picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our women's college basketball best bets, the top play to make on this game is IUPUI +22.5 at the spread.

IUPUI vs. Northwestern game-day updates and essential details

Wednesday's women's college basketball game between Northwestern and IUPUI at Welsh-Ryan Arena is scheduled to commence at 8:00PM ET.

• Who: IUPUI vs. Northwestern
• Date: Wednesday, November 5, 2025
• Time: 8:00PM ET/5:00PM PT
• Venue: Welsh-Ryan Arena

Conclusion

We predict Northwestern, with a 96% win probability, will likely beat IUPUI on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate IUPUI vs. Northwestern insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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