Iowa vs. Purdue prediction: Why Purdue is favored to win men's college basketball matchup [1/14/2026]

Men's college basketball action continues on Wednesday at 6:30 PM ET as Iowa squares off with Purdue in men's college basketball action at Mackey Arena.

Based on updated simulation results, Dimers' advanced college basketball model predicts Purdue as the most likely winner of the Iowa vs. Purdue game.

This article offers a closer look at Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Iowa vs. Purdue prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the outcome of Wednesday's NCAA basketball game between Iowa and Purdue 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model gives Purdue an 84% chance of defeating Iowa. Our predicted final score has Purdue winning 78-67.

According to our model, the bookies have got it right, and Iowa and Purdue each have a 50% chance of covering the spread, while the 142.5-point over/under has a 54% chance of going over.

Iowa vs. Purdue odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Iowa vs. Purdue picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: