Iowa State vs. Houston prediction: Iowa State favored to win women's college basketball matchup [12/31/2025]

Houston and Iowa State are scheduled to meet in the women's college basketball at Fertitta Center on Wednesday, with tipoff at 2:00 PM ET.

Based on updated simulations, Dimers' new women's basketball model projects Iowa State as the most likely winner of the Iowa State vs. Houston game.

This article offers an expanded analysis of Wednesday's matchup, including best bets and picks.

Iowa State vs. Houston prediction: Who will win?

Using innovative machine learning and statistical analysis, we have simulated the result of Wednesday's women's basketball matchup between Iowa State and Houston 10,000 times as part of our women's college basketball predictions coverage.

Our leading predictive model gives Iowa State a 98% chance of defeating Houston.

According to our model, the over/under total of 142.5 points has a 52% chance of staying under.

Iowa State vs. Houston odds

We have researched the best women's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Iowa State vs. Houston picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: