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Iowa State vs. Houston prediction: Iowa State favored to win women's college basketball matchup [12/31/2025]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Iowa State vs Houston predictions for college basketball Wednesday.
Houston and Iowa State are scheduled to meet in the women's college basketball at Fertitta Center on Wednesday, with tipoff at 2:00 PM ET.
Based on updated simulations, Dimers' new women's basketball model projects Iowa State as the most likely winner of the Iowa State vs. Houston game.
This article offers a closer look at Wednesday's matchup, including best bets and picks.
Iowa State vs. Houston prediction: Who will win?
Using trusted machine learning and data analysis, we have simulated the outcome of Wednesday's women's basketball game between Iowa State and Houston 10,000 times as part of our women's college basketball predictions coverage.
Our independent predictive model gives Iowa State a 98% chance of beating Houston.
According to our model, the over/under total of 142.5 points has a 52% chance of staying under.
Iowa State vs. Houston odds
We have researched the best women's college basketball odds in America for this game, which are listed here:
| Bet Type | Iowa State | Houston |
|---|---|---|
| Spread | -28.5 (-114) | +28.5 (-114) |
| Moneyline | -100000 | +5000 |
| Total | o142.5 (-110) | u142.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Iowa State vs. Houston picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Houston +28.5 | -114 |
| Moneyline | Houston | +5000 |
| Total | Under 142.5 | -110 |
According to our women's college basketball best bets, the top play to make on this game is Houston +28.5 at the spread.
Iowa State vs. Houston game-day updates and essential details
Wednesday's women's basketball game between Houston and Iowa State at Fertitta Center is scheduled to start at 2:00 PM ET.
- Who: Iowa State vs. Houston
- Date: Wednesday, December 31, 2025
- Time: 2:00 PM ET/11:00AM PT
- Venue: Fertitta Center
Conclusion
We predict Iowa State, with a 98% win probability, will likely beat Houston on Wednesday.
AI and automation have enhanced this article to quickly deliver accurate Iowa State vs. Houston insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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