Iowa State vs. Cincinnati prediction: Why Iowa State is favored to win men's college basketball matchup [1/17/2026]

Men's college basketball action continues on Saturday at 2:00 PM ET as the favored Iowa State locks horns with Cincinnati in men's college basketball action at Fifth Third Arena.

Based on the latest simulations, Dimers' advanced college basketball model predicts Iowa State as the most likely winner of the Iowa State vs. Cincinnati game.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Iowa State vs. Cincinnati prediction: Who will win and cover?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Saturday's NCAA basketball matchup between Iowa State and Cincinnati 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model gives Iowa State a 74% chance of defeating Cincinnati. Our predicted final score has Iowa State winning 74-67.

According to our model, Cincinnati (+7.5) has a 60% chance of covering the spread, while the 141.5-point over/under has an equal 50-50 chance of hitting.

Iowa State vs. Cincinnati odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Iowa State vs. Cincinnati picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: