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Iowa State vs. Cincinnati prediction: Why Iowa State is favored to win men's college basketball matchup [1/17/2026]

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Written by Dave Garofolo

Get Iowa State vs Cincinnati predictions for college basketball Saturday.

Iowa State-Cincinnati Predictions and Game Preview.
Iowa State vs. Cincinnati men's college basketball prediction for Saturday, January 17, 2026.

Cincinnati will take on the favored Iowa State in men's college basketball action at Fifth Third Arena on Saturday, beginning at 2:00 PM ET.

Based on the latest simulation results, Dimers' proven college basketball model predicts Iowa State as the most likely winner of the Iowa State vs. Cincinnati game.

This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Iowa State vs. Cincinnati prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the outcome of Saturday's NCAA basketball matchup between Iowa State and Cincinnati 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Iowa State a 68% chance of beating Cincinnati. Our predicted final score has Iowa State winning 73-69.

According to our model, Cincinnati (+5.5) has a 55% chance of covering the spread, while the 141.5-point over/under has a 52% chance of going over.

 

Iowa State vs. Cincinnati odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

Bet Type Iowa State Cincinnati
Spread -5.5 (-105) +5.5 (-110)
Moneyline -235 +210
Total o141.5 (-110) u141.5 (-108)

All odds are correct at the time of publication and are subject to change.

Iowa State vs. Cincinnati picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Cincinnati +5.5 -110
Moneyline Cincinnati +210
Total Over 141.5 -110

According to our men's college basketball best bets, the top play to make on this game is Cincinnati +5.5 at the spread.

 

Iowa State vs. Cincinnati game-day updates and essential details

Saturday's men's college basketball action between Cincinnati and Iowa State at Fifth Third Arena is scheduled to begin at 2:00 PM ET.

  • Who: Iowa State vs. Cincinnati
  • Date: Saturday, January 17, 2026
  • Time: 2:00 PM ET/11:00AM PT
  • Venue: Fifth Third Arena

Conclusion

We predict Iowa State, with a 68% win probability, will likely beat Cincinnati on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Iowa State vs. Cincinnati insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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