Indianapolis Colts vs. Seattle Seahawks updated prediction featuring Jonathan Taylor, Jaxon Smith-Njigba [Week 15, 2025]

Dimers' latest NFL predictions are live for Seattle Seahawks vs. Indianapolis Colts in Week 15, with our model giving the Seahawks an 89% of winning.

As Sunday approaches, both teams have updated their injury reports. Some lineup calls are still undecided, and those could shape how each side approaches this cross-conference meeting.

Since our early Seahawks-Colts predictions, we’ve updated the win probabilities, score projections, and TD odds for Jonathan Taylor, Jaxon Smith-Njigba, and others.

For the full simulation breakdown—including spreads, totals, touchdown probabilities, and the full list of player props—check out our Colts vs. Seahawks page.

What's changed? Indianapolis vs. Seattle updated predictions

Our NFL predictions model has been re-run with the newest available data, creating a clearer picture of how this Colts vs. Seahawks matchup stacks up. Here are the updated forecasts:

• Straight Up Win Probabilities: Colts 11%, Seahawks 89%
• Predicted Final Score: Colts 15-27 Seahawks
• Spread: Colts (+13.5) 54%, Seahawks (-13.5) 46%
• Total Points (42.5): Over 54%, Under 46%

As of December 11, 2025, these Colts-Seahawks figures reflect changes since our early-week simulation.

Anytime touchdown scorer predictions

New NFL player projections for Week 15 highlight the top candidates to find the end zone in Colts-Seahawks on Sunday:

Indianapolis Colts

• Jonathan Taylor: 54.6% probability
• Tyler Warren: 21.5% probability
• Michael Pittman: 20.3% probability

Seattle Seahawks

• Jaxon Smith-Njigba: 49.0% probability
• Zach Charbonnet: 46.4% probability
• Kenneth Walker: 46.0% probability

Colts vs. Seahawks latest odds

The best current odds from the top sportsbooks in the US:

• Spread: Colts +13.5 (-105), Seahawks -13.5 (-115)
• Moneyline: Colts +750, Seahawks -1050
• Total: Over/Under 42.5 (-108/-110)

Odds are correct at time of publication and are subject to change—track live updates via our NFL odds page.

Colts vs. Seahawks Week 15 details

The NFL Week 15 matchup between the Seahawks and Colts at Lumen Field is scheduled for December 14, 2025.

• Who: Indianapolis Colts vs. Seattle Seahawks
• Date: Sunday, December 14, 2025
• Time: 4:25PM ET/1:25PM PT
• Venue: Lumen Field

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Conclusion

We predict the Seahawks, with an 89% win probability, will likely beat the Colts in Week 15 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Colts vs. Seahawks game, with human oversight maintaining high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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