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Colts vs. Seahawks prediction: Seattle favored to win in NFL Week 15 [2025]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Get Indianapolis Colts vs Seattle Seahawks predictions for NFL Sunday.
The Seattle Seahawks and Indianapolis Colts are scheduled to meet in Week 15 of the NFL season at Lumen Field on Sunday, starting at 4:25PM ET.
Based on the latest simulation results, Dimers' proven NFL model projects the Seahawks as the most likely winner of the Colts vs. Seahawks game.
This article offers further insights into this week's matchup, including projected touchdown scorers, best bets and player prop picks.
Colts vs. Seahawks prediction: Who will win and cover?
Since our Colts-Seahawks predictions earlier in the week, we have simulated the outcome of Sunday's NFL game between the Colts and Seahawks 10,000 times as part of our NFL predictions coverage.
Our famous predictive model gives the Seahawks an 89% chance of defeating the Colts in Week 15 of the NFL season. Our predicted final score has the Seahawks winning 27-14.
According to our model, the Colts (+13.5) have a 54% chance of covering the spread, while the over/under total of 41.5 points has a 54% chance of going over.
To see win probabilities for every matchup this week, check out our expert NFL Week 15 straight up picks.
Colts vs. Seahawks odds
We have researched the best NFL odds in America for this game, which are listed here:
| Bet Type | Colts | Seahawks |
|---|---|---|
| Spread | +13.5 (-102) | -13.5 (-120) |
| Moneyline | +810 | -1100 |
| Total | o41.5 (-110) | u41.5 (-108) |
All odds are correct at the time of publication and are subject to change.
Colts vs. Seahawks picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Colts +13.5 | -102 |
| Moneyline | Colts | +810 |
| Total | Over 41.5 | -110 |
According to our best NFL bets, the top play to make on this game is Colts +13.5 at the spread.
Colts vs. Seahawks TD scorers
Who will score a touchdown in Colts vs. Seahawks?
According to our list of touchdown scorer predictions for today, Jonathan Taylor is most likely to score an anytime touchdown in Colts vs. Seahawks.
Our projections give Taylor a 53.5% chance of getting in for six at Lumen Field, while the wide receiver is a 12.2% chance of scoring the first touchdown the game.
Anytime touchdown scorer predictions
Indianapolis Colts
| Player | Anytime TD Probability |
|---|---|
| Jonathan Taylor (RB) | 53.5% |
| Michael Pittman (WR) | 22.1% |
| Tyler Warren (TE) | 22.0% |
| Alec Pierce (WR) | 18.7% |
| Josh Downs (WR) | 18.0% |
Seattle Seahawks
| Player | Anytime TD Probability |
|---|---|
| Jaxon Smith-Njigba (WR) | 47.5% |
| Kenneth Walker (RB) | 45.8% |
| Zach Charbonnet (RB) | 43.7% |
| AJ Barner (TE) | 30.5% |
| Rashid Shaheed (WR) | 22.4% |
First touchdown scorer predictions
Indianapolis Colts
| Player | First TD Probability |
|---|---|
| Jonathan Taylor (RB) | 12.2% |
| Michael Pittman (WR) | 4.0% |
| Tyler Warren (TE) | 4.0% |
| Alec Pierce (WR) | 3.3% |
| Josh Downs (WR) | 3.2% |
Seattle Seahawks
| Player | First TD Probability |
|---|---|
| Jaxon Smith-Njigba (WR) | 12.8% |
| Kenneth Walker (RB) | 12.1% |
| Zach Charbonnet (RB) | 11.4% |
| AJ Barner (TE) | 7.2% |
| Rashid Shaheed (WR) | 5.0% |
Colts vs Seahawks player props
Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Colts and Seahawks. Head to our NFL player projections page now to access a full list of player prop projections for every offensive player in this matchup and all other Week 15 games.
Quarterbacks
Of the starting quarterbacks, the Colts' Philip Rivers is projected to have a quiet game with 171 passing yards. The Seahawks' Sam Darnold is expected to throw for 231 yards.
| Player | Proj. Pass Yards |
|---|---|
| Philip Rivers (IND) | 171 |
| Sam Darnold (SEA) | 231 |
Colts rushing
| Player | Proj. Rush Yards |
|---|---|
| Jonathan Taylor | 83 |
| Ameer Abdullah | 6 |
| Tyler Goodson | 5 |
Seahawks rushing
| Player | Proj. Rush Yards |
|---|---|
| Kenneth Walker | 62 |
| Zach Charbonnet | 39 |
| Sam Darnold | 6 |
Colts receiving
| Player | Proj. Rec. Yards |
|---|---|
| Michael Pittman | 39 |
| Tyler Warren | 38 |
| Alec Pierce | 34 |
| Josh Downs | 28 |
| Jonathan Taylor | 20 |
Seahawks receiving
| Player | Proj. Rec. Yards |
|---|---|
| Jaxon Smith-Njigba | 99 |
| Cooper Kupp | 38 |
| Rashid Shaheed | 35 |
| AJ Barner | 34 |
| Kenneth Walker | 17 |
Colts vs. Seahawks game-day updates and essential details
The NFL Week 15 game between the Seahawks and Colts at Lumen Field is scheduled to begin at 4:25PM ET.
- Who: Indianapolis Colts vs. Seattle Seahawks
- Date: Sunday, December 14, 2025
- Time: 4:25PM ET/1:25PM PT
- Venue: Lumen Field
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Conclusion
We predict the Seahawks, with an 89% win probability, will likely beat the Colts in Week 15 of the NFL season.
AI and automation have enhanced this article to quickly deliver accurate Colts vs. Seahawks insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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