Indianapolis Colts vs. Jacksonville Jaguars updated prediction featuring Jonathan Taylor, Travis Etienne [Week 14, 2025]

Dimers' latest NFL predictions are live for Jacksonville Jaguars vs. Indianapolis Colts in Week 14, with our model giving the Colts a 57% of winning.

As Sunday approaches, both teams have updated their injury reports. Some lineup calls are still undecided, and those could shape how each side approaches this AFC South clash.

Since our early Jaguars-Colts predictions, we’ve updated the win probabilities, score projections, and TD odds for Jonathan Taylor, Travis Etienne, and others.

For the full simulation breakdown—including spreads, totals, touchdown probabilities, and the full list of player props—head to our Colts vs. Jaguars page.

What's changed? Indianapolis vs. Jacksonville updated predictions

Our NFL predictions model has been re-run with the newest available data, creating a clearer picture of how this Colts vs. Jaguars matchup stacks up. Here are the updated forecasts:

• Straight Up Win Probabilities: Colts 57%, Jaguars 43%
• Predicted Final Score: Colts 24-22 Jaguars
• Spread: Colts (-1.5) 50%, Jaguars (+1.5) 50%
• Total Points (47.5): Over 46%, Under 54%

As of December 4, 2025, these Colts-Jaguars numbers reflect changes since our early-week simulation.

Anytime touchdown scorer predictions

New NFL player projections for Week 14 highlight the top candidates to find the end zone in Colts-Jaguars on Sunday:

Indianapolis Colts

• Jonathan Taylor: 67.0% probability
• Tyler Warren: 30.9% probability
• Michael Pittman: 29.8% probability

Jacksonville Jaguars

• Travis Etienne: 42.6% probability
• Bhayshul Tuten: 33.5% probability
• Jakobi Meyers: 30.0% probability

Colts vs. Jaguars latest odds

The best current odds from the top sportsbooks in the US:

• Spread: Colts -1.5 (-110), Jaguars +1.5 (-108)
• Moneyline: Colts -125, Jaguars +110
• Total: Over/Under 47.5 (-110/-105)

Odds are correct at time of publication and are subject to change—track live updates via our NFL odds page.

Colts vs. Jaguars Week 14 details

The NFL Week 14 game between the Jaguars and Colts at EverBank Stadium is scheduled for December 7, 2025.

• Who: Indianapolis Colts vs. Jacksonville Jaguars
• Date: Sunday, December 7, 2025
• Time: 1:00PM ET/10:00AM PT
• Venue: EverBank Stadium

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Conclusion

We predict the Colts, with a 57% win probability, will likely beat the Jaguars in Week 14 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Colts vs. Jaguars game, with human oversight maintaining high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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