Indianapolis Colts vs. Jacksonville Jaguars: Experts release early Week 14 predictions [2025]

The Indianapolis Colts and Jacksonville Jaguars will meet in Week 14 of the NFL season at EverBank Stadium on Sunday, December 7, 2025, starting at 1:00PM ET.

Initial simulations from Dimers' trusted NFL model favor the Colts as the most likely winner of this AFC South rivalry clash.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Colts vs. Jaguars predictions page.

Indianapolis vs. Jacksonville early predictions

Leveraging trusted machine learning and analysis, we have simulated the Colts vs. Jaguars game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight up win probabilities: Colts 59%, Jaguars 41%
• Predicted final score: Colts 24-21 Jaguars
• Spread: Colts (-1.5) 53%, Jaguars (+1.5) 47%
• Total points (48.5): Over 43%, Under 57%

As of December 1, 2025, these Colts-Jaguars figures and predictions reflect the latest data and insights available.

Colts vs. Jaguars Week 14 details

The NFL Week 14 action between the Jaguars and Colts at EverBank Stadium is scheduled for December 7, 2025.

• Who: Indianapolis Colts vs. Jacksonville Jaguars
• Date: Sunday, December 7, 2025
• Time: 1:00PM ET/10:00AM PT
• Venue: EverBank Stadium

Colts vs. Jaguars opening odds

We've researched the best betting odds across America for this Week 14 game, which are listed here:

• Spread: Colts -1.5 (-110), Jaguars +1.5 (-105)
• Moneyline: Colts -122, Jaguars +114
• Total: Over/Under 48.5 (-108/-112)

Odds may continue to move—track live changes via our NFL odds page.

Anytime touchdown scorer predictions

Early NFL player projections for Week 14 highlight the top candidates to score a TD in Colts-Jaguars in Week 14:

Indianapolis Colts

• Jonathan Taylor: 76.7% probability
• Michael Pittman: 31.6% probability
• Daniel Jones: 29.5% probability

Jacksonville Jaguars

• Travis Etienne: 47.6% probability
• Bhayshul Tuten: 36.5% probability
• Brian Thomas: 32.9% probability

Colts vs Jaguars player props

Jonathan Taylor is projected to lead rushing for the Colts, while Travis Etienne is expected to pace the Jaguars on the ground.

In the receiving game, our projections favor Indianapolis' Michael Pittman and Jacksonville's Brian Thomas as the likely leaders for each team.

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Conclusion

We predict the Colts, with a 59% win probability, will likely beat the Jaguars in Week 14 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Colts vs. Jaguars game, with human oversight maintaining high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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