Indiana vs. Michigan State prediction: Why Michigan State is favored to win men's college basketball matchup [1/13/2026]

Men's college basketball action continues on Tuesday at 7:00 PM ET as Indiana takes on Michigan State in men's college basketball action at Jack Breslin Students Events Center.

Based on the latest simulation results, Dimers' advanced college basketball model predicts Michigan State as the most likely winner of the Indiana vs. Michigan State game.

This article offers further insights into Tuesday's matchup, including an expanded look at the predicted score, best bets and picks.

Indiana vs. Michigan State prediction: Who will win and cover?

Using powerful machine learning and data analysis, we have simulated the result of Tuesday's NCAA basketball game between Indiana and Michigan State 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model currently gives Michigan State a 79% chance of beating Indiana. Our predicted final score has Michigan State winning 77-68.

According to our model, Michigan State (-7.5) has a 55% chance of covering the spread, while the over/under total of 144.5 points has a 52% chance of going over.

Indiana vs. Michigan State odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Indiana vs. Michigan State picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: