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Indiana vs. Illinois prediction: Why Illinois is favored to win women's college basketball matchup [12/6/2025]
Get Indiana vs Illinois predictions for college basketball Saturday.

Illinois and Indiana will lock horns in the women's college basketball at State Farm Center on Saturday, with tipoff at 12:00PM ET.
Based on updated simulation results, Dimers' new women's basketball model predicts Illinois as the most likely winner of the Indiana vs. Illinois game.
This article offers further insights into Saturday's matchup, including best bets and picks.
Indiana vs. Illinois prediction: Who will win?
Using powerful machine learning and data analysis, we have simulated the outcome of Saturday's women's basketball game between Indiana and Illinois 10,000 times as part of our women's college basketball predictions coverage.
Our leading predictive model currently gives Illinois a 59% chance of defeating Indiana.
According to our model, the 132.5-point over/under has a 53% chance of staying under.
Indiana vs. Illinois odds
We have sourced the best women's college basketball odds in America for this game, which are listed here:
| Bet Type | Indiana | Illinois |
|---|---|---|
| Spread | +4.5 (-110) | -4.5 (-110) |
| Moneyline | +172 | -192 |
| Total | o132.5 (-110) | u132.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Indiana vs. Illinois picks and best bet
After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Indiana +4.5 | -110 |
| Moneyline | Indiana | +172 |
| Total | Under 132.5 | -110 |
According to our women's college basketball best bets, the top play to make on this game is Indiana +4.5 at the spread.
Indiana vs. Illinois game-day updates and essential details
Saturday's women's basketball matchup between Illinois and Indiana at State Farm Center is scheduled to start at 12:00PM ET.
- Who: Indiana vs. Illinois
- Date: Saturday, December 6, 2025
- Time: 12:00PM ET/9:00AM PT
- Venue: State Farm Center
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Conclusion
We predict Illinois, with a 59% win probability, will likely beat Indiana on Saturday.
AI and automation have enhanced this article to quickly deliver accurate Indiana vs. Illinois insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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