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Indiana State vs. Louisiana Tech prediction: Louisiana Tech favored to win men's college basketball matchup [11/26/2025]

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Written by Mac Douglass

Get Indiana State vs Louisiana Tech predictions for college basketball Wednesday.

Indiana State-Louisiana Tech Predictions and Game Preview.
Indiana State vs. Louisiana Tech men's college basketball prediction for Wednesday, November 26, 2025.

Louisiana Tech will take on Indiana State in men's college basketball action at Thomas Assembly Center on Wednesday, beginning at 7:30PM ET.

Based on the latest simulations, Dimers' advanced college basketball model projects Louisiana Tech as the most likely winner of the Indiana State vs. Louisiana Tech game.

This article offers further insights into Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Indiana State vs. Louisiana Tech prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the result of Wednesday's NCAA basketball game between Indiana State and Louisiana Tech 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model currently gives Louisiana Tech a 66% chance of defeating Indiana State. Our predicted final score has Louisiana Tech winning 72-68.

According to our model, Louisiana Tech (-2.5) has a 58% chance of covering the spread, while the 140.5-point over/under has a 52% chance of going over.

 

Indiana State vs. Louisiana Tech odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

Bet Type Indiana State Louisiana Tech
Spread +2.5 (-105) -2.5 (-110)
Moneyline +126 -148
Total o140.5 (-110) u140.5 (-110)

All odds are correct at the time of publication and are subject to change.

Indiana State vs. Louisiana Tech picks and best bet

After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Louisiana Tech -2.5 -110
Moneyline Louisiana Tech -148
Total Over 140.5 -110

According to our best men's college basketball bets, the top play to make on this game is Louisiana Tech to win.

 

Indiana State vs. Louisiana Tech game-day updates and essential details

Wednesday's men's college basketball game between Louisiana Tech and Indiana State at Thomas Assembly Center is scheduled to commence at 7:30PM ET.

  • Who: Indiana State vs. Louisiana Tech
  • Date: Wednesday, November 26, 2025
  • Time: 7:30PM ET/4:30PM PT
  • Venue: Thomas Assembly Center

 

Conclusion

We predict Louisiana Tech, with a 66% win probability, will likely beat Indiana State on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Indiana State vs. Louisiana Tech insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Mac Douglass
Senior Editor

Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.

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