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Indiana State vs. Illinois State prediction: Why Illinois State is favored to win men's college basketball matchup [12/21/2025]

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Written by Jason Bevilacqua

Get Indiana State vs Illinois State predictions for college basketball Sunday.

Indiana State-Illinois State Predictions and Game Preview.
Indiana State vs. Illinois State men's college basketball prediction for Sunday, December 21, 2025.

Illinois State and Indiana State are scheduled to meet in men's college basketball action at CEFCU Arena on Sunday, starting at 5:00 PM ET.

Based on the latest simulations, Dimers' proven college basketball model predicts Illinois State as the most likely winner of the Indiana State vs. Illinois State game.

This article offers a closer look at Sunday's matchup, including an expanded look at the predicted score, best bets and picks.

Indiana State vs. Illinois State prediction: Who will win and cover?

Using trusted machine learning and data analysis, we have simulated the outcome of Sunday's NCAA basketball matchup between Indiana State and Illinois State 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model currently gives Illinois State a 90% chance of beating Indiana State. Our predicted final score has Illinois State winning 83-69.

According to our model, Illinois State (-13.5) has a 53% chance of covering the spread, while the over/under total of 152.5 points has a 54% chance of staying under.

 

Indiana State vs. Illinois State odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

Bet Type Indiana State Illinois State
Spread +13.5 (-110) -13.5 (-105)
Moneyline +680 -950
Total o152.5 (-110) u152.5 (-105)

All odds are correct at the time of publication and are subject to change.

Indiana State vs. Illinois State picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Illinois State -13.5 -105
Moneyline Illinois State -950
Total Under 152.5 -105

According to our men's college basketball best bets, the top play to make on this game is Under 152.5 total points.

 

Indiana State vs. Illinois State game-day updates and essential details

Sunday's men's college basketball game between Illinois State and Indiana State at CEFCU Arena is scheduled to begin at 5:00 PM ET.

  • Who: Indiana State vs. Illinois State
  • Date: Sunday, December 21, 2025
  • Time: 5:00 PM ET/2:00PM PT
  • Venue: CEFCU Arena

Conclusion

We predict Illinois State, with a 90% win probability, will likely beat Indiana State on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Indiana State vs. Illinois State insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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