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Indiana State vs. Illinois State prediction: Why Illinois State is favored to win men's college basketball matchup [12/21/2025]
Get Indiana State vs Illinois State predictions for college basketball Sunday.

Men's college basketball action continues on Sunday at 5:00 PM ET as Indiana State takes on the favored Illinois State in men's college basketball action at CEFCU Arena.
Based on updated simulation results, Dimers' proven college basketball model predicts Illinois State as the most likely winner of the Indiana State vs. Illinois State game.
This article offers an expanded analysis of Sunday's matchup, including an expanded look at the predicted score, best bets and picks.
Indiana State vs. Illinois State prediction: Who will win and cover?
Using powerful machine learning and data analysis, we have simulated the outcome of Sunday's NCAA basketball matchup between Indiana State and Illinois State 10,000 times as part of our men's college basketball predictions coverage.
Our leading predictive model currently gives Illinois State an 89% chance of beating Indiana State. Our predicted final score has Illinois State winning 82-68.
According to our model, Illinois State (-13.5) has a 52% chance of covering the spread, while the 152.5-point over/under has an equal 50-50 chance of hitting.
Indiana State vs. Illinois State odds
We have sourced the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Indiana State | Illinois State |
|---|---|---|
| Spread | +13.5 (-110) | -13.5 (-108) |
| Moneyline | +740 | -950 |
| Total | o152.5 (-105) | u152.5 (-115) |
All odds are correct at the time of publication and are subject to change.
Indiana State vs. Illinois State picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Illinois State -13.5 | -108 |
| Moneyline | Illinois State | -950 |
| Total | Over 152.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is Illinois State -13.5 at the spread.
Indiana State vs. Illinois State game-day updates and essential details
Sunday's men's college basketball matchup between Illinois State and Indiana State at CEFCU Arena is scheduled to start at 5:00 PM ET.
- Who: Indiana State vs. Illinois State
- Date: Sunday, December 21, 2025
- Time: 5:00 PM ET/2:00PM PT
- Venue: CEFCU Arena
Conclusion
We predict Illinois State, with an 89% win probability, will likely beat Indiana State on Sunday.
AI and automation have enhanced this article to quickly deliver accurate Indiana State vs. Illinois State insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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