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Indiana State vs. Illinois State prediction: Why Illinois State is favored to win men's college basketball matchup [12/21/2025]

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Written by Jason Bevilacqua

Get Indiana State vs Illinois State predictions for college basketball Sunday.

Indiana State-Illinois State Predictions and Game Preview.
Indiana State vs. Illinois State men's college basketball prediction for Sunday, December 21, 2025.

Men's college basketball action continues on Sunday at 5:00 PM ET as Indiana State takes on the favored Illinois State in men's college basketball action at CEFCU Arena.

Based on updated simulation results, Dimers' proven college basketball model predicts Illinois State as the most likely winner of the Indiana State vs. Illinois State game.

This article offers an expanded analysis of Sunday's matchup, including an expanded look at the predicted score, best bets and picks.

Indiana State vs. Illinois State prediction: Who will win and cover?

Using powerful machine learning and data analysis, we have simulated the outcome of Sunday's NCAA basketball matchup between Indiana State and Illinois State 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model currently gives Illinois State an 89% chance of beating Indiana State. Our predicted final score has Illinois State winning 82-68.

According to our model, Illinois State (-13.5) has a 52% chance of covering the spread, while the 152.5-point over/under has an equal 50-50 chance of hitting.

 

Indiana State vs. Illinois State odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

Bet Type Indiana State Illinois State
Spread +13.5 (-110) -13.5 (-108)
Moneyline +740 -950
Total o152.5 (-105) u152.5 (-115)

All odds are correct at the time of publication and are subject to change.

Indiana State vs. Illinois State picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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