Pacers vs. Grizzlies prediction: Why Indiana is favored to win Saturday's NBA matchup [10/25/2025]

The Memphis Grizzlies will face the Indiana Pacers in NBA action at FedExForum on Saturday, beginning at 8:00PM ET.

Based on the latest simulation results and today’s injury news, Dimers' advanced NBA model predicts the Pacers as the most likely winner of the Pacers vs. Grizzlies game.

This prediction follows the latest NBA Injury Report, which suggests the Grizzlies lineup will feature stars like Ja Morant, Jaren Jackson and Santi Aldama, while the Pacers will rely on Pascal Siakam, Bennedict Mathurin and Obi Toppin.

This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Pacers vs. Grizzlies prediction: Who will win, cover the spread?

Using innovative machine learning and data analysis, we have simulated the outcome of Saturday's NBA game between the Pacers and Grizzlies 10,000 times as part of our NBA predictions coverage.

Our famous predictive model currently gives the Pacers a 54% chance of beating the Grizzlies. Our predicted final score has the Pacers winning 118-117.

According to our model, the Grizzlies (-1) have a 53% chance of covering the spread, while the 237.5-point over/under has a 54% chance of staying under.

Pacers vs. Grizzlies odds

We have researched the best NBA odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Pacers vs. Grizzlies picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our NBA best bets, the top play to make on this game is Pacers moneyline.

Pacers vs. Grizzlies player props

NBA prop bets are an enjoyable way to wager on Saturday's Pacers vs. Grizzlies game without necessarily betting on the outcome. We have crunched the numbers to project how each team's leading players will perform at FedExForum.

Pascal Siakam is expected to lead the Pacers with 23 points, 8 rebounds and 4 assists, while Ja Morant is projected to have 26 points, 4 rebounds and 7 assists for the Grizzlies.

Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and more, for every game this season.

Pacers prediction

Our model's projected player stats for the Pacers are:

Grizzlies prediction

Projected points, rebounds, assists and three-pointers made for the Grizzlies:

Pacers vs. Grizzlies game-day updates and essential details

Saturday's game between the Grizzlies and Pacers at FedExForum is scheduled to begin at 8:00PM ET.

• Who: Indiana Pacers vs. Memphis Grizzlies
• Date: Saturday, October 25, 2025
• Time: 8:00PM ET/5:00PM PT
• Venue: FedExForum

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Conclusion

We predict the Pacers, with a 54% win probability, will likely beat the Grizzlies on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Pacers vs. Grizzlies insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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